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Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis.
Mukhopadhyay P, Rajesh M, Cao Z, Horváth B, Park O, Wang H, Erdelyi K, Holovac E, Wang Y, Liaudet L, Hamdaoui N, Lafdil F, Haskó G, Szabo C, Boulares AH, Gao B, Pacher P. Mukhopadhyay P, et al. Among authors: liaudet l. Hepatology. 2014 May;59(5):1998-2009. doi: 10.1002/hep.26763. Epub 2014 Apr 1. Hepatology. 2014. PMID: 24089324 Free PMC article.
Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis.
Rajesh M, Mukhopadhyay P, Bátkai S, Godlewski G, Haskó G, Liaudet L, Pacher P. Rajesh M, et al. Among authors: liaudet l. Biochem Biophys Res Commun. 2006 Nov 17;350(2):352-7. doi: 10.1016/j.bbrc.2006.09.049. Epub 2006 Sep 20. Biochem Biophys Res Commun. 2006. PMID: 17007818 Free PMC article.
Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.
Rajesh M, Mukhopadhyay P, Godlewski G, Bátkai S, Haskó G, Liaudet L, Pacher P. Rajesh M, et al. Among authors: liaudet l. Biochem Biophys Res Commun. 2006 Dec 1;350(4):1056-62. doi: 10.1016/j.bbrc.2006.09.160. Epub 2006 Oct 9. Biochem Biophys Res Commun. 2006. PMID: 17046715 Free PMC article.
PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis.
Mukhopadhyay P, Horváth B, Rajesh M, Varga ZV, Gariani K, Ryu D, Cao Z, Holovac E, Park O, Zhou Z, Xu MJ, Wang W, Godlewski G, Paloczi J, Nemeth BT, Persidsky Y, Liaudet L, Haskó G, Bai P, Boulares AH, Auwerx J, Gao B, Pacher P. Mukhopadhyay P, et al. Among authors: liaudet l. J Hepatol. 2017 Mar;66(3):589-600. doi: 10.1016/j.jhep.2016.10.023. Epub 2016 Oct 29. J Hepatol. 2017. PMID: 27984176
235 results