Liefke R - Search Results

1

Enhancer-driven transcriptional regulation is a potential key determinant for human visceral and subcutaneous adipocytes.

Liefke R, Bokelmann K, Ghadimi BM, Dango S. Liefke R, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Jun 30:S1874-9399(18)30095-6. doi: 10.1016/j.bbagrm.2018.06.007. Online ahead of print. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 29966764

2

The oxidative demethylase ALKBH3 marks hyperactive gene promoters in human cancer cells.

Liefke R, Windhof-Jaidhauser IM, Gaedcke J, Salinas-Riester G, Wu F, Ghadimi M, Dango S. Liefke R, et al. Genome Med. 2015 Jun 30;7(1):66. doi: 10.1186/s13073-015-0180-0. eCollection 2015. Genome Med. 2015. PMID: 26221185 Free PMC article.

3

The CpG Island-Binding Protein SAMD1 Contributes to an Unfavorable Gene Signature in HepG2 Hepatocellular Carcinoma Cells.

Simon C, Stielow B, Nist A, Rohner I, Weber LM, Geller M, Fischer S, Stiewe T, Liefke R. Simon C, et al. Among authors: liefke r. Biology (Basel). 2022 Apr 6;11(4):557. doi: 10.3390/biology11040557. Biology (Basel). 2022. PMID: 35453756 Free PMC article.

4

IRF8 Is an AML-Specific Susceptibility Factor That Regulates Signaling Pathways and Proliferation of AML Cells.

Liss F, Frech M, Wang Y, Giel G, Fischer S, Simon C, Weber LM, Nist A, Stiewe T, Neubauer A, Burchert A, Liefke R. Liss F, et al. Among authors: liefke r. Cancers (Basel). 2021 Feb 12;13(4):764. doi: 10.3390/cancers13040764. Cancers (Basel). 2021. PMID: 33673123 Free PMC article.

5

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.

Stielow B, Zhou Y, Cao Y, Simon C, Pogoda HM, Jiang J, Ren Y, Phanor SK, Rohner I, Nist A, Stiewe T, Hammerschmidt M, Shi Y, Bulyk ML, Wang Z, Liefke R. Stielow B, et al. Among authors: liefke r. Sci Adv. 2021 May 12;7(20):eabf2229. doi: 10.1126/sciadv.abf2229. Print 2021 May. Sci Adv. 2021. PMID: 33980486 Free PMC article.

6

Polycomb-like Proteins in Gene Regulation and Cancer.

Fischer S, Liefke R. Fischer S, et al. Among authors: liefke r. Genes (Basel). 2023 Apr 18;14(4):938. doi: 10.3390/genes14040938. Genes (Basel). 2023. PMID: 37107696 Free PMC article. Review.

7

Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells.

Fischer S, Trinh VT, Simon C, Weber LM, Forné I, Nist A, Bange G, Abendroth F, Stiewe T, Steinchen W, Liefke R, Vázquez O. Fischer S, et al. Among authors: liefke r. Cell Chem Biol. 2023 Jul 20;30(7):766-779.e11. doi: 10.1016/j.chembiol.2023.05.012. Epub 2023 Jun 23. Cell Chem Biol. 2023. PMID: 37354906

8

NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression.

Riedlinger T, Liefke R, Meier-Soelch J, Jurida L, Nist A, Stiewe T, Kracht M, Schmitz ML. Riedlinger T, et al. Among authors: liefke r. FASEB J. 2019 Mar;33(3):4188-4202. doi: 10.1096/fj.201801638R. Epub 2018 Dec 7. FASEB J. 2019. PMID: 30526044 Free PMC article.

This suggests a mechanism of assisted p65 chromatin association that can be in part facilitated by chromatin priming and cooperativity with other transcription factors such as AP-1.-Riedlinger, T., Liefke, R., Meier-Soelch, J., Jurida, L., Nist, A., Stiewe, T., Krac …

This suggests a mechanism of assisted p65 chromatin association that can be in part facilitated by chromatin priming and cooperativity with …

9

Evolutionary adaptation of the Polycomb repressive complex 2.

Fischer S, Weber LM, Liefke R. Fischer S, et al. Among authors: liefke r. Epigenetics Chromatin. 2022 Feb 22;15(1):7. doi: 10.1186/s13072-022-00439-6. Epigenetics Chromatin. 2022. PMID: 35193659 Free PMC article. Review.

10

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

Weber LM, Jia Y, Stielow B, Gisselbrecht SS, Cao Y, Ren Y, Rohner I, King J, Rothman E, Fischer S, Simon C, Forné I, Nist A, Stiewe T, Bulyk ML, Wang Z, Liefke R. Weber LM, et al. Among authors: liefke r. Nucleic Acids Res. 2023 Jan 25;51(2):574-594. doi: 10.1093/nar/gkac1188. Nucleic Acids Res. 2023. PMID: 36537216 Free PMC article.

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