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Chemical genomics reveals targetable programs of human cancers rooted in pluripotency.
Orlando L, Benoit YD, Reid JC, Nakanishi M, Boyd AL, García-Rodriguez JL, Tanasijevic B, Doyle MS, Luchman A, Restall IJ, Bergin CJ, Masibag AN, Aslostovar L, Di Lu J, Laronde S, Collins TJ, Weiss S, Bhatia M. Orlando L, et al. Among authors: aslostovar l. Cell Chem Biol. 2023 Jul 20;30(7):780-794.e8. doi: 10.1016/j.chembiol.2023.06.004. Epub 2023 Jun 27. Cell Chem Biol. 2023. PMID: 37379846
Sam68 Allows Selective Targeting of Human Cancer Stem Cells.
Benoit YD, Mitchell RR, Risueño RM, Orlando L, Tanasijevic B, Boyd AL, Aslostovar L, Salci KR, Shapovalova Z, Russell J, Eguchi M, Golubeva D, Graham M, Xenocostas A, Trus MR, Foley R, Leber B, Collins TJ, Bhatia M. Benoit YD, et al. Among authors: aslostovar l. Cell Chem Biol. 2017 Jul 20;24(7):833-844.e9. doi: 10.1016/j.chembiol.2017.05.026. Epub 2017 Jun 22. Cell Chem Biol. 2017. PMID: 28648376 Free article.
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.
Benoit YD, Mitchell RR, Wang W, Orlando L, Boyd AL, Tanasijevic B, Aslostovar L, Shapovalova Z, Doyle M, Bergin CJ, Vojnits K, Casado FL, Di Lu J, Porras DP, García-Rodriguez JL, Russell J, Zouggar A, Masibag AN, Caba C, Koteva K, Kinthada LK, Patel JS, Andres SN, Magolan J, Collins TJ, Wright GD, Bhatia M. Benoit YD, et al. Among authors: aslostovar l. Cell Chem Biol. 2021 Oct 21;28(10):1394-1406.e10. doi: 10.1016/j.chembiol.2021.04.014. Epub 2021 May 11. Cell Chem Biol. 2021. PMID: 33979648 Free PMC article.
Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche.
Boyd AL, Reid JC, Salci KR, Aslostovar L, Benoit YD, Shapovalova Z, Nakanishi M, Porras DP, Almakadi M, Campbell CJV, Jackson MF, Ross CA, Foley R, Leber B, Allan DS, Sabloff M, Xenocostas A, Collins TJ, Bhatia M. Boyd AL, et al. Among authors: aslostovar l. Nat Cell Biol. 2017 Nov;19(11):1336-1347. doi: 10.1038/ncb3625. Epub 2017 Oct 16. Nat Cell Biol. 2017. PMID: 29035359