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AMPK negatively regulates tensin-dependent integrin activity.
Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, Yan Y, Sahgal P, Lerche M, Manneville JB, Mäkelä TP, Ivaska J. Georgiadou M, et al. Among authors: lilja j. J Cell Biol. 2017 Apr 3;216(4):1107-1121. doi: 10.1083/jcb.201609066. Epub 2017 Mar 13. J Cell Biol. 2017. PMID: 28289092 Free PMC article.
Integrin activity in neuronal connectivity.
Lilja J, Ivaska J. Lilja J, et al. J Cell Sci. 2018 Jun 15;131(12):jcs212803. doi: 10.1242/jcs.212803. J Cell Sci. 2018. PMID: 29907643 Free article. Review.
SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
Lilja J, Zacharchenko T, Georgiadou M, Jacquemet G, De Franceschi N, Peuhu E, Hamidi H, Pouwels J, Martens V, Nia FH, Beifuss M, Boeckers T, Kreienkamp HJ, Barsukov IL, Ivaska J. Lilja J, et al. Nat Cell Biol. 2017 Apr;19(4):292-305. doi: 10.1038/ncb3487. Epub 2017 Mar 6. Nat Cell Biol. 2017. PMID: 28263956 Free PMC article.
SORLA regulates endosomal trafficking and oncogenic fitness of HER2.
Pietilä M, Sahgal P, Peuhu E, Jäntti NZ, Paatero I, Närvä E, Al-Akhrass H, Lilja J, Georgiadou M, Andersen OM, Padzik A, Sihto H, Joensuu H, Blomqvist M, Saarinen I, Boström PJ, Taimen P, Ivaska J. Pietilä M, et al. Among authors: lilja j. Nat Commun. 2019 May 28;10(1):2340. doi: 10.1038/s41467-019-10275-0. Nat Commun. 2019. PMID: 31138794 Free PMC article.
Sortilin-related receptor is a druggable therapeutic target in breast cancer.
Al-Akhrass H, Pietilä M, Lilja J, Vesilahti EM, Anttila JM, Haikala HM, Munne PM, Klefström J, Peuhu E, Ivaska J. Al-Akhrass H, et al. Among authors: lilja j. Mol Oncol. 2022 Jan;16(1):116-129. doi: 10.1002/1878-0261.13106. Epub 2021 Oct 10. Mol Oncol. 2022. PMID: 34564954 Free PMC article.
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling.
Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani Nia F, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp HJ, Lappalainen P, Ivaska J. Salomaa SI, et al. Among authors: lilja j. Curr Biol. 2021 Nov 22;31(22):4956-4970.e9. doi: 10.1016/j.cub.2021.09.022. Epub 2021 Oct 4. Curr Biol. 2021. PMID: 34610274 Free article.
A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites.
McCormick B, Craig HE, Chu JY, Carlin LM, Canel M, Wollweber F, Toivakka M, Michael M, Astier AL, Norton L, Lilja J, Felton JM, Sasaki T, Ivaska J, Hers I, Dransfield I, Rossi AG, Vermeren S. McCormick B, et al. Among authors: lilja j. J Immunol. 2019 Sep 15;203(6):1579-1588. doi: 10.4049/jimmunol.1900443. Epub 2019 Aug 19. J Immunol. 2019. PMID: 31427445 Free PMC article.
204 results