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Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.
Burkard C, Lillico SG, Reid E, Jackson B, Mileham AJ, Ait-Ali T, Whitelaw CB, Archibald AL. Burkard C, et al. Among authors: lillico sg. PLoS Pathog. 2017 Feb 23;13(2):e1006206. doi: 10.1371/journal.ppat.1006206. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28231264 Free PMC article.
Transgenic sheep designed for transplantation studies.
Ritchie WA, King T, Neil C, Carlisle AJ, Lillico S, McLachlan G, Whitelaw CB. Ritchie WA, et al. Mol Reprod Dev. 2009 Jan;76(1):61-4. doi: 10.1002/mrd.20930. Mol Reprod Dev. 2009. PMID: 18449866
Milk lacking α-casein leads to permanent reduction in body size in mice.
Kolb AF, Huber RC, Lillico SG, Carlisle A, Robinson CJ, Neil C, Petrie L, Sorensen DB, Olsson IA, Whitelaw CB. Kolb AF, et al. Among authors: lillico sg. PLoS One. 2011;6(7):e21775. doi: 10.1371/journal.pone.0021775. Epub 2011 Jul 18. PLoS One. 2011. PMID: 21789179 Free PMC article.
Ovine-induced pluripotent stem cells can contribute to chimeric lambs.
Sartori C, DiDomenico AI, Thomson AJ, Milne E, Lillico SG, Burdon TG, Whitelaw CB. Sartori C, et al. Among authors: lillico sg. Cell Reprogram. 2012 Feb;14(1):8-19. doi: 10.1089/cell.2011.0050. Epub 2012 Jan 4. Cell Reprogram. 2012. PMID: 22217199
Efficient TALEN-mediated gene knockout in livestock.
Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, Christian M, Voytas DF, Long CR, Whitelaw CB, Fahrenkrug SC. Carlson DF, et al. Among authors: lillico sg. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17382-7. doi: 10.1073/pnas.1211446109. Epub 2012 Oct 1. Proc Natl Acad Sci U S A. 2012. PMID: 23027955 Free PMC article.
Live pigs produced from genome edited zygotes.
Lillico SG, Proudfoot C, Carlson DF, Stverakova D, Neil C, Blain C, King TJ, Ritchie WA, Tan W, Mileham AJ, McLaren DG, Fahrenkrug SC, Whitelaw CB. Lillico SG, et al. Sci Rep. 2013 Oct 10;3:2847. doi: 10.1038/srep02847. Sci Rep. 2013. PMID: 24108318 Free PMC article.
58 results