Lin HS - Search Results

1

Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1.

Huang LY, Lee YS, Huang JJ, Chang CC, Chang JM, Chuang SH, Kao KJ, Tsai YJ, Tsai PY, Liu CW, Lin HS, Lau JY. Huang LY, et al. Among authors: lin hs. J Exp Clin Cancer Res. 2014 Jan 9;33(1):6. doi: 10.1186/1756-9966-33-6. J Exp Clin Cancer Res. 2014. PMID: 24401611 Free PMC article.

2

Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo.

Huang LY, Chang CC, Lee YS, Chang JM, Huang JJ, Chuang SH, Kao KJ, Lau GM, Tsai PY, Liu CW, Lin HS, Lau JY. Huang LY, et al. Among authors: lin hs. Mol Cancer Ther. 2014 Jun;13(6):1419-30. doi: 10.1158/1535-7163.MCT-13-0700. Epub 2014 Apr 2. Mol Cancer Ther. 2014. PMID: 24694948

3

Discovery of 4-aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 inhibitors. Part I: optimization of in vitro potencies and pharmacokinetic properties.

Lee YS, Chuang SH, Huang LY, Lai CL, Lin YH, Yang JY, Liu CW, Yang SC, Lin HS, Chang CC, Lai JY, Jian PS, Lam K, Chang JM, Lau JY, Huang JJ. Lee YS, et al. Among authors: lin yh, lin hs. J Med Chem. 2014 May 22;57(10):4098-110. doi: 10.1021/jm401990s. Epub 2014 May 7. J Med Chem. 2014. PMID: 24773549

4

Inhibition of Hec1 as a novel approach for treatment of primary liver cancer.

Huang LY, Chang CC, Lee YS, Huang JJ, Chuang SH, Chang JM, Kao KJ, Lau GM, Tsai PY, Liu CW, Lin HS, Gish RG, Lau JY. Huang LY, et al. Among authors: lin hs. Cancer Chemother Pharmacol. 2014 Sep;74(3):511-20. doi: 10.1007/s00280-014-2540-7. Epub 2014 Jul 20. Cancer Chemother Pharmacol. 2014. PMID: 25038613

5

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.

Chuang SH, Lee YE, Huang LYL, Chen CK, Lai CL, Lin YH, Yang JY, Yang SC, Chang LH, Chen CH, Liu CW, Lin HS, Lee YR, Huang KP, Fu KC, Jen HM, Lai JY, Jian PS, Wang YC, Hsueh WY, Tsai PY, Hong WH, Chang CC, Wu DZ, Wu J, Chen MH, Yu KM, Chern CY, Chang JM, Lau JYN, Huang JJ. Chuang SH, et al. Among authors: lin yh, lin hs. Eur J Med Chem. 2020 Apr 1;191:112118. doi: 10.1016/j.ejmech.2020.112118. Epub 2020 Feb 7. Eur J Med Chem. 2020. PMID: 32113126

6

Copper(I)-Catalyzed Nitrile-Addition/N-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6H-indolo[3,2-c]quinolin-6-ones as Potent Topoisomerase-I Inhibitors.

Hsueh WY, Lee YE, Huang MS, Lai CH, Gao YS, Lin JC, Chen YF, Chang CL, Chou SY, Chen SF, Lu YY, Chang LH, Lin SF, Lin YH, Hsu PC, Wei WY, Huang YC, Kao YF, Teng LW, Liu HH, Chen YC, Yuan TT, Chan YW, Huang PH, Chao YT, Huang SY, Jian BH, Huang HY, Yang SC, Lo TH, Huang GR, Wang SY, Lin HS, Chuang SH, Huang JJ. Hsueh WY, et al. Among authors: lin sf, lin yh, lin jc, lin hs. J Med Chem. 2021 Feb 11;64(3):1435-1453. doi: 10.1021/acs.jmedchem.0c00727. Epub 2021 Jan 25. J Med Chem. 2021. PMID: 33492141

7

Plant polysaccharide-derived edible film packaging for instant food: Rapid dissolution in hot water coupled with exceptional mechanical and barrier characteristics.

Yang YC, Lin HS, Chen HX, Wang PK, Zheng BD, Huang YY, Zhang N, Zhang XQ, Ye J, Xiao MT. Yang YC, et al. Among authors: lin hs. Int J Biol Macromol. 2024 May 3:132066. doi: 10.1016/j.ijbiomac.2024.132066. Online ahead of print. Int J Biol Macromol. 2024. PMID: 38705323

8

The varicella-zoster virus ORF16 protein promotes both the nuclear transport and the protein abundance of the viral DNA polymerase subunit ORF28.

Lin HS, Li CH, Chen LW, Wang SS, Chen LY, Hung CH, Lin CL, Chang PJ. Lin HS, et al. Virus Res. 2024 Apr 26;345:199379. doi: 10.1016/j.virusres.2024.199379. Online ahead of print. Virus Res. 2024. PMID: 38643859 Free PMC article.

9

Neutralizing antibodies to interferon alfa arising during peginterferon therapy of chronic hepatitis B in children and adults: Results from the HBRN trials.

Zahoor MA, Feld JB, Lin HS, Mosa AI, Salimzadeh L, Perrillo RP, Chung RT, Schwarz KB, Janssen H, Gehring AJ, Feld JJ. Zahoor MA, et al. Among authors: lin hs. Hepatology. 2024 Apr 17. doi: 10.1097/HEP.0000000000000878. Online ahead of print. Hepatology. 2024. PMID: 38630448

10

A Novel Digital Health Platform With Health Coaches to Optimize Surgical Patients: Feasibility Study at a Large Academic Health System.

Esper SA, Holder-Murray J, Meister KA, Lin HS, Hamilton DK, Groff YJ, Zuckerbraun BS, Mahajan A. Esper SA, et al. Among authors: lin hs. JMIR Perioper Med. 2024 Apr 4;7:e52125. doi: 10.2196/52125. JMIR Perioper Med. 2024. PMID: 38573737 Free PMC article.

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