Ling K - Search Results

1

Sarm1 haploinsufficiency or low expression levels after antisense oligonucleotides delay programmed axon degeneration.

Gould SA, Gilley J, Ling K, Jafar-Nejad P, Rigo F, Coleman M. Gould SA, et al. Among authors: ling k. Cell Rep. 2021 Dec 14;37(11):110108. doi: 10.1016/j.celrep.2021.110108. Cell Rep. 2021. PMID: 34910914 Free PMC article.

2

TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals.

Sahashi K, Hua Y, Ling KK, Hung G, Rigo F, Horev G, Katsuno M, Sobue G, Ko CP, Bennett CF, Krainer AR. Sahashi K, et al. Among authors: ling kk. Genes Dev. 2012 Aug 15;26(16):1874-84. doi: 10.1101/gad.197418.112. Genes Dev. 2012. PMID: 22895255 Free PMC article.

3

Pathological impact of SMN2 mis-splicing in adult SMA mice.

Sahashi K, Ling KK, Hua Y, Wilkinson JE, Nomakuchi T, Rigo F, Hung G, Xu D, Jiang YP, Lin RZ, Ko CP, Bennett CF, Krainer AR. Sahashi K, et al. Among authors: ling kk. EMBO Mol Med. 2013 Oct;5(10):1586-601. doi: 10.1002/emmm.201302567. Epub 2013 Sep 9. EMBO Mol Med. 2013. PMID: 24014320 Free PMC article.

4

Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.

Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, Lardelli R, Sundararaman B, Donohue JP, Javaherian A, Lykke-Andersen J, Finkbeiner S, Bennett CF, Ares M Jr, Burge CB, Taylor JP, Rigo F, Yeo GW. Martinez FJ, et al. Among authors: ling k. Neuron. 2016 Nov 23;92(4):780-795. doi: 10.1016/j.neuron.2016.09.050. Epub 2016 Oct 20. Neuron. 2016. PMID: 27773581 Free PMC article.

5

The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy.

d'Ydewalle C, Ramos DM, Pyles NJ, Ng SY, Gorz M, Pilato CM, Ling K, Kong L, Ward AJ, Rubin LL, Rigo F, Bennett CF, Sumner CJ. d'Ydewalle C, et al. Among authors: ling k. Neuron. 2017 Jan 4;93(1):66-79. doi: 10.1016/j.neuron.2016.11.033. Epub 2016 Dec 22. Neuron. 2017. PMID: 28017471 Free PMC article.

6

Antisense-mediated reduction of EphA4 in the adult CNS does not improve the function of mice with amyotrophic lateral sclerosis.

Ling KK, Jackson M, Alkam D, Liu D, Allaire N, Sun C, Kiaei M, McCampbell A, Rigo F. Ling KK, et al. Neurobiol Dis. 2018 Jun;114:174-183. doi: 10.1016/j.nbd.2018.03.002. Epub 2018 Mar 6. Neurobiol Dis. 2018. PMID: 29518482 Free PMC article.

7

An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis.

Gertsman I, Wuu J, McAlonis-Downes M, Ghassemian M, Ling K, Rigo F, Bennett F, Benatar M, Miller TM, Da Cruz S. Gertsman I, et al. Among authors: ling k. JCI Insight. 2019 May 16;4(10):e122768. doi: 10.1172/jci.insight.122768. eCollection 2019 May 16. JCI Insight. 2019. PMID: 31092730 Free PMC article.

8

NCALD Antisense Oligonucleotide Therapy in Addition to Nusinersen further Ameliorates Spinal Muscular Atrophy in Mice.

Torres-Benito L, Schneider S, Rombo R, Ling KK, Grysko V, Upadhyay A, Kononenko NL, Rigo F, Bennett CF, Wirth B. Torres-Benito L, et al. Among authors: ling kk. Am J Hum Genet. 2019 Jul 3;105(1):221-230. doi: 10.1016/j.ajhg.2019.05.008. Epub 2019 Jun 20. Am J Hum Genet. 2019. PMID: 31230718 Free PMC article.

9

Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS.

Ghadge GD, Sonobe Y, Camarena A, Drigotas C, Rigo F, Ling KK, Roos RP. Ghadge GD, et al. Among authors: ling kk. Neurobiol Dis. 2020 Mar;136:104702. doi: 10.1016/j.nbd.2019.104702. Epub 2019 Dec 16. Neurobiol Dis. 2020. PMID: 31837419 Free article.

10

Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination.

Lai F, Damle SS, Ling KK, Rigo F. Lai F, et al. Among authors: ling kk. Mol Cell. 2020 Mar 5;77(5):1032-1043.e4. doi: 10.1016/j.molcel.2019.12.029. Epub 2020 Jan 7. Mol Cell. 2020. PMID: 31924447 Free article.

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