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Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain.
Thromb Res. 2015 May;135(5):977-83. doi: 10.1016/j.thromres.2015.01.025. Epub 2015 Jan 26.
Thromb Res. 2015.
PMID: 25747820
Free article.
VKORC1 and VKORC1L1 have distinctly different oral anticoagulant dose-response characteristics and binding sites.
Czogalla KJ, Liphardt K, Höning K, Hornung V, Biswas A, Watzka M, Oldenburg J.
Czogalla KJ, et al. Among authors: liphardt k.
Blood Adv. 2018 Mar 27;2(6):691-702. doi: 10.1182/bloodadvances.2017006775.
Blood Adv. 2018.
PMID: 29581108
Free PMC article.
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Warfarin and vitamin K compete for binding to Phe55 in human VKOR.
Czogalla KJ, Biswas A, Höning K, Hornung V, Liphardt K, Watzka M, Oldenburg J.
Czogalla KJ, et al. Among authors: liphardt k.
Nat Struct Mol Biol. 2017 Jan;24(1):77-85. doi: 10.1038/nsmb.3338. Epub 2016 Dec 12.
Nat Struct Mol Biol. 2017.
PMID: 27941861
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Variants in FIX propeptide associated with vitamin K antagonist hypersensitivity: functional analysis and additional data confirming the common founder mutations.
Pezeshkpoor B, Czogalla KJ, Caspers M, Berkemeier AC, Liphardt K, Ghosh S, Kellner M, Ulrich S, Pavlova A, Oldenburg J.
Pezeshkpoor B, et al. Among authors: liphardt k.
Ann Hematol. 2018 Jun;97(6):1061-1069. doi: 10.1007/s00277-018-3264-2. Epub 2018 Feb 15.
Ann Hematol. 2018.
PMID: 29450643
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Selective Modulation of the Protease Activated Protein C Using Exosite Inhibiting Aptamers.
Hamedani NS, Müller J, Tolle F, Rühl H, Pezeshkpoor B, Liphardt K, Oldenburg J, Mayer G, Pötzsch B.
Hamedani NS, et al. Among authors: liphardt k.
Nucleic Acid Ther. 2020 Oct;30(5):276-288. doi: 10.1089/nat.2020.0844. Epub 2020 Jun 2.
Nucleic Acid Ther. 2020.
PMID: 32486960
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Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A.
Bachelet D, Albert T, Mbogning C, Hässler S, Zhang Y, Schultze-Strasser S, Repessé Y, Rayes J, Pavlova A, Pezeshkpoor B, Liphardt K, Davidson JE, Hincelin-Méry A, Dönnes P, Lacroix-Desmazes S, Königs C, Oldenburg J, Broët P; ABIRISK consortium.
Bachelet D, et al. Among authors: liphardt k.
PLoS One. 2019 Jun 13;14(6):e0218258. doi: 10.1371/journal.pone.0218258. eCollection 2019.
PLoS One. 2019.
PMID: 31194850
Free PMC article.
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Galpha(q)-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors.
ter Braak M, Danneberg K, Lichte K, Liphardt K, Ktistakis NT, Pitson SM, Hla T, Jakobs KH, Meyer zu Heringdorf D.
ter Braak M, et al. Among authors: liphardt k.
Biochim Biophys Acta. 2009 May;1791(5):357-70. doi: 10.1016/j.bbalip.2009.01.019.
Biochim Biophys Acta. 2009.
PMID: 19830907
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