Liu N - Search Results

1

Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment.

Qi Z, Xu Z, Zhang L, Zou Y, Li J, Yan W, Li C, Liu N, Wu H. Qi Z, et al. Among authors: liu n. Nat Commun. 2022 Jan 10;13(1):182. doi: 10.1038/s41467-021-27833-0. Nat Commun. 2022. PMID: 35013322 Free PMC article.

2

TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT.

Hill R, Madureira PA, Ferreira B, Baptista I, Machado S, Colaço L, Dos Santos M, Liu N, Dopazo A, Ugurel S, Adrienn A, Kiss-Toth E, Isbilen M, Gure AO, Link W. Hill R, et al. Among authors: liu n. Nat Commun. 2017 Mar 9;8:14687. doi: 10.1038/ncomms14687. Nat Commun. 2017. PMID: 28276427 Free PMC article. Retracted.

3

Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439.

Zou Y, Qi Z, Guo W, Zhang L, Ruscetti M, Shenoy T, Liu N, Wu H. Zou Y, et al. Among authors: liu n. Mol Cancer Ther. 2018 Oct;17(10):2091-2099. doi: 10.1158/1535-7163.MCT-18-0038. Epub 2018 Jul 25. Mol Cancer Ther. 2018. PMID: 30045927 Free PMC article.

4

T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1.

Zhu H, Zhang L, Wu Y, Dong B, Guo W, Wang M, Yang L, Fan X, Tang Y, Liu N, Lei X, Wu H. Zhu H, et al. Among authors: liu n. Elife. 2018 Nov 9;7:e38314. doi: 10.7554/eLife.38314. Elife. 2018. PMID: 30412053 Free PMC article.

5

Simultaneous Inhibition of PI3Kδ and PI3Kα Induces ABC-DLBCL Regression by Blocking BCR-Dependent and -Independent Activation of NF-κB and AKT.

Paul J, Soujon M, Wengner AM, Zitzmann-Kolbe S, Sturz A, Haike K, Keng Magdalene KH, Tan SH, Lange M, Tan SY, Mumberg D, Lim ST, Ziegelbauer K, Liu N. Paul J, et al. Among authors: liu n. Cancer Cell. 2017 Jan 9;31(1):64-78. doi: 10.1016/j.ccell.2016.12.003. Cancer Cell. 2017. PMID: 28073005 Free article.

6

Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses.

Heller S, Glaeske S, Gluske K, Paul J, Böhme A, Janzer A, Roider HG, Montebaur A, Nicke B, Lesche R, von Ahsen O, Politz O, Liu N, Gorjánácz M. Heller S, et al. Among authors: liu n. Clin Exp Med. 2023 Dec;23(8):5445-5461. doi: 10.1007/s10238-023-01227-6. Epub 2023 Nov 8. Clin Exp Med. 2023. PMID: 37935952 Free PMC article.

7

Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946).

Scott WJ, Hentemann MF, Rowley RB, Bull CO, Jenkins S, Bullion AM, Johnson J, Redman A, Robbins AH, Esler W, Fracasso RP, Garrison T, Hamilton M, Michels M, Wood JE, Wilkie DP, Xiao H, Levy J, Stasik E, Liu N, Schaefer M, Brands M, Lefranc J. Scott WJ, et al. Among authors: liu n. ChemMedChem. 2016 Jul 19;11(14):1517-30. doi: 10.1002/cmdc.201600148. Epub 2016 Jun 16. ChemMedChem. 2016. PMID: 27310202 Free PMC article.

8

Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth.

Petrova E, Scholz A, Paul J, Sturz A, Haike K, Siegel F, Mumberg D, Liu N. Petrova E, et al. Among authors: liu n. Oncotarget. 2017 Jul 25;8(30):48660-48670. doi: 10.18632/oncotarget.12650. Oncotarget. 2017. PMID: 27750213 Free PMC article.

9

BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models.

Liu N, Rowley BR, Bull CO, Schneider C, Haegebarth A, Schatz CA, Fracasso PR, Wilkie DP, Hentemann M, Wilhelm SM, Scott WJ, Mumberg D, Ziegelbauer K. Liu N, et al. Mol Cancer Ther. 2013 Nov;12(11):2319-30. doi: 10.1158/1535-7163.MCT-12-0993-T. Epub 2013 Oct 29. Mol Cancer Ther. 2013. PMID: 24170767

10

Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS-ERK signaling.

Will M, Qin AC, Toy W, Yao Z, Rodrik-Outmezguine V, Schneider C, Huang X, Monian P, Jiang X, de Stanchina E, Baselga J, Liu N, Chandarlapaty S, Rosen N. Will M, et al. Among authors: liu n. Cancer Discov. 2014 Mar;4(3):334-47. doi: 10.1158/2159-8290.CD-13-0611. Epub 2014 Jan 16. Cancer Discov. 2014. PMID: 24436048 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

12,281 results

Search Page