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Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.
Su D, Wang W, Hou Y, Wang L, Yi X, Cao C, Wang Y, Gao H, Wang Y, Yang C, Liu B, Chen X, Wu X, Wu J, Yan D, Wei S, Han L, Liu S, Wang Q, Shi L, Shan L. Su D, et al. Among authors: liu s, liu b. Nucleic Acids Res. 2021 May 7;49(8):4421-4440. doi: 10.1093/nar/gkab209. Nucleic Acids Res. 2021. PMID: 33849069 Free PMC article.
Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis.
He L, Liu X, Yang J, Li W, Liu S, Liu X, Yang Z, Ren J, Wang Y, Shan L, Guan C, Pei F, Lei L, Zhang Y, Yi X, Yang X, Liang J, Liu R, Sun L, Shang Y. He L, et al. Among authors: liu x, liu s, liu r. Cell Res. 2018 Sep;28(9):934-951. doi: 10.1038/s41422-018-0079-6. Epub 2018 Aug 22. Cell Res. 2018. PMID: 30135474 Free PMC article.
Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis.
Yang C, Wu J, Liu X, Wang Y, Liu B, Chen X, Wu X, Yan D, Han L, Liu S, Shan L, Shang Y. Yang C, et al. Among authors: liu x, liu s, liu b. Cancer Res. 2020 Oct 1;80(19):4114-4128. doi: 10.1158/0008-5472.CAN-20-0493. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651256
UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.
Liu X, Xu B, Yang J, He L, Zhang Z, Cheng X, Yu H, Liu X, Jin T, Peng Y, Huang Y, Xia L, Wang Y, Wu J, Wu X, Liu S, Shan L, Yang X, Sun L, Liang J, Zhang Y, Shang Y. Liu X, et al. Among authors: liu s. Mol Cell. 2021 Jul 15;81(14):2960-2974.e7. doi: 10.1016/j.molcel.2021.05.022. Epub 2021 Jun 9. Mol Cell. 2021. PMID: 34111398 Free article.
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry.
Liu X, Si W, He L, Yang J, Peng Y, Ren J, Liu X, Jin T, Yu H, Zhang Z, Cheng X, Zhang W, Xia L, Huang Y, Wang Y, Liu S, Shan L, Zhang Y, Yang X, Li H, Liang J, Sun L, Shang Y. Liu X, et al. Among authors: liu s. Signal Transduct Target Ther. 2021 Nov 3;6(1):375. doi: 10.1038/s41392-021-00774-2. Signal Transduct Target Ther. 2021. PMID: 34728602 Free PMC article.
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