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Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment.
Vail ME, Murone C, Tan A, Hii L, Abebe D, Janes PW, Lee FT, Baer M, Palath V, Bebbington C, Yarranton G, Llerena C, Garic S, Abramson D, Cartwright G, Scott AM, Lackmann M. Vail ME, et al. Among authors: llerena c. Cancer Res. 2014 Aug 15;74(16):4470-81. doi: 10.1158/0008-5472.CAN-14-0218. Cancer Res. 2014. PMID: 25125683
An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
Atapattu L, Saha N, Chheang C, Eissman MF, Xu K, Vail ME, Hii L, Llerena C, Liu Z, Horvay K, Abud HE, Kusebauch U, Moritz RL, Ding BS, Cao Z, Rafii S, Ernst M, Scott AM, Nikolov DB, Lackmann M, Janes PW. Atapattu L, et al. Among authors: llerena c. J Exp Med. 2016 Aug 22;213(9):1741-57. doi: 10.1084/jem.20151095. Epub 2016 Aug 8. J Exp Med. 2016. PMID: 27503072 Free PMC article.
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
Frick R, Høydahl LS, Petersen J, du Pré MF, Kumari S, Berntsen G, Dewan AE, Jeliazkov JR, Gunnarsen KS, Frigstad T, Vik ES, Llerena C, Lundin KEA, Yaqub S, Jahnsen J, Gray JJ, Rossjohn J, Sollid LM, Sandlie I, Løset GÅ. Frick R, et al. Among authors: llerena c. Sci Immunol. 2021 Aug 20;6(62):eabg4925. doi: 10.1126/sciimmunol.abg4925. Sci Immunol. 2021. PMID: 34417258 Free PMC article.
The cryo-EM structure of the endocytic receptor DEC-205.
Gully BS, Venugopal H, Fulcher AJ, Fu Z, Li J, Deuss FA, Llerena C, Heath WR, Lahoud MH, Caminschi I, Rossjohn J, Berry R. Gully BS, et al. Among authors: llerena c. J Biol Chem. 2021 Jan-Jun;296:100127. doi: 10.1074/jbc.RA120.016451. Epub 2020 Dec 3. J Biol Chem. 2021. PMID: 33257321 Free PMC article.
71 results