Lockyer PJ - Search Results

1

Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo.

Lockyer PJ, Wennström S, Kupzig S, Venkateswarlu K, Downward J, Cullen PJ. Lockyer PJ, et al. Curr Biol. 1999 Mar 11;9(5):265-8. doi: 10.1016/s0960-9822(99)80116-x. Curr Biol. 1999. PMID: 10074452 Free article.

2

GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins.

Kupzig S, Deaconescu D, Bouyoucef D, Walker SA, Liu Q, Polte CL, Daumke O, Ishizaki T, Lockyer PJ, Wittinghofer A, Cullen PJ. Kupzig S, et al. Among authors: lockyer pj. J Biol Chem. 2006 Apr 14;281(15):9891-900. doi: 10.1074/jbc.M512802200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431904 Free PMC article.

3

Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting.

Lockyer PJ, Bottomley JR, Reynolds JS, McNulty TJ, Venkateswarlu K, Potter BV, Dempsey CE, Cullen PJ. Lockyer PJ, et al. Curr Biol. 1997 Dec 1;7(12):1007-10. doi: 10.1016/s0960-9822(06)00423-4. Curr Biol. 1997. PMID: 9382842 Free article.

4

Structural and functional analysis of the putative inositol 1,3,4, 5-tetrakisphosphate receptors GAP1(IP4BP) and GAP1(m).

Bottomley JR, Reynolds JS, Lockyer PJ, Cullen PJ. Bottomley JR, et al. Among authors: lockyer pj. Biochem Biophys Res Commun. 1998 Sep 8;250(1):143-9. doi: 10.1006/bbrc.1998.9179. Biochem Biophys Res Commun. 1998. PMID: 9735347

5

GAP1IP4BP contains a novel group I pleckstrin homology domain that directs constitutive plasma membrane association.

Cozier GE, Lockyer PJ, Reynolds JS, Kupzig S, Bottomley JR, Millard TH, Banting G, Cullen PJ. Cozier GE, et al. Among authors: lockyer pj. J Biol Chem. 2000 Sep 8;275(36):28261-8. doi: 10.1074/jbc.M000469200. J Biol Chem. 2000. PMID: 10869341 Free article.

6

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

Lockyer PJ, Kupzig S, Cullen PJ. Lockyer PJ, et al. Curr Biol. 2001 Jun 26;11(12):981-6. doi: 10.1016/s0960-9822(01)00261-5. Curr Biol. 2001. PMID: 11448776 Free article.

7

Tissue-specific expression and endogenous subcellular distribution of the inositol 1,3,4,5-tetrakisphosphate-binding proteins GAP1(IP4BP) and GAP1(m).

Lockyer PJ, Vanlingen S, Reynolds JS, McNulty TJ, Irvine RF, Parys JB, Cullen PJ. Lockyer PJ, et al. Biochem Biophys Res Commun. 1999 Feb 16;255(2):421-6. doi: 10.1006/bbrc.1999.0217. Biochem Biophys Res Commun. 1999. PMID: 10049724

8

Integration of calcium and Ras signalling.

Cullen PJ, Lockyer PJ. Cullen PJ, et al. Among authors: lockyer pj. Nat Rev Mol Cell Biol. 2002 May;3(5):339-48. doi: 10.1038/nrm808. Nat Rev Mol Cell Biol. 2002. PMID: 11988768 Review.

9

Analyzing the role of the putative inositol 1,3,4,5-tetrakisphosphate receptor GAP1IP4BP in intracellular Ca2+ homeostasis.

Walker SA, Kupzig S, Lockyer PJ, Bilu S, Zharhary D, Cullen PJ. Walker SA, et al. Among authors: lockyer pj. J Biol Chem. 2002 Dec 13;277(50):48779-85. doi: 10.1074/jbc.M204839200. Epub 2002 Sep 27. J Biol Chem. 2002. PMID: 12356770 Free article.

10

Control of Ras cycling by Ca2+.

Walker SA, Cullen PJ, Taylor JA, Lockyer PJ. Walker SA, et al. Among authors: lockyer pj. FEBS Lett. 2003 Jul 3;546(1):6-10. doi: 10.1016/s0014-5793(03)00412-5. FEBS Lett. 2003. PMID: 12829229 Free article. Review.

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