Lopez-Haber C - Search Results

1

Rac signaling in breast cancer: a tale of GEFs and GAPs.

Wertheimer E, Gutierrez-Uzquiza A, Rosemblit C, Lopez-Haber C, Sosa MS, Kazanietz MG. Wertheimer E, et al. Cell Signal. 2012 Feb;24(2):353-362. doi: 10.1016/j.cellsig.2011.08.011. Epub 2011 Aug 27. Cell Signal. 2012. PMID: 21893191 Free PMC article. Review.

2

Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.

Sosa MS, Lopez-Haber C, Yang C, Wang H, Lemmon MA, Busillo JM, Luo J, Benovic JL, Klein-Szanto A, Yagi H, Gutkind JS, Parsons RE, Kazanietz MG. Sosa MS, et al. Mol Cell. 2010 Dec 22;40(6):877-92. doi: 10.1016/j.molcel.2010.11.029. Mol Cell. 2010. PMID: 21172654 Free PMC article.

3

Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon.

Caino MC, Lopez-Haber C, Kissil JL, Kazanietz MG. Caino MC, et al. PLoS One. 2012;7(2):e31714. doi: 10.1371/journal.pone.0031714. Epub 2012 Feb 27. PLoS One. 2012. PMID: 22384062 Free PMC article.

4

Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.

Lopez-Haber C, Kazanietz MG. Lopez-Haber C, et al. Mol Pharmacol. 2013 May;83(5):1141-54. doi: 10.1124/mol.112.084293. Epub 2013 Mar 11. Mol Pharmacol. 2013. PMID: 23478800 Free PMC article.

5

Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α.

Lopez-Haber C, Barrio-Real L, Casado-Medrano V, Kazanietz MG. Lopez-Haber C, et al. Mol Cell Biol. 2016 Jul 14;36(15):2011-26. doi: 10.1128/MCB.00180-16. Print 2016 Aug 1. Mol Cell Biol. 2016. PMID: 27185877 Free PMC article.

6

The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses.

Kazanietz MG, Barrio-Real L, Casado-Medrano V, Baker MJ, Lopez-Haber C. Kazanietz MG, et al. Among authors: lopez haber c. Small GTPases. 2018 Jul 4;9(4):297-303. doi: 10.1080/21541248.2016.1221273. Epub 2016 Sep 2. Small GTPases. 2018. PMID: 27588611 Free PMC article. Review.

7

The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic.

Casado-Medrano V, Baker MJ, Lopez-Haber C, Cooke M, Wang S, Caloca MJ, Kazanietz MG. Casado-Medrano V, et al. Among authors: lopez haber c. Biochem Soc Trans. 2018 Aug 20;46(4):1003-1012. doi: 10.1042/BST20170519. Epub 2018 Jul 31. Biochem Soc Trans. 2018. PMID: 30065108 Free PMC article. Review.

8

Proteins kinase Cɛ is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes.

Caino MC, Lopez-Haber C, Kim J, Mochly-Rosen D, Kazanietz MG. Caino MC, et al. Oncogene. 2012 May 17;31(20):2593-600. doi: 10.1038/onc.2011.428. Epub 2011 Sep 26. Oncogene. 2012. PMID: 21996750 Free PMC article.

9

Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins.

Wang H, Gutierrez-Uzquiza A, Garg R, Barrio-Real L, Abera MB, Lopez-Haber C, Rosemblit C, Lu H, Abba M, Kazanietz MG. Wang H, et al. J Biol Chem. 2014 Jul 11;289(28):19823-38. doi: 10.1074/jbc.M114.548446. Epub 2014 May 13. J Biol Chem. 2014. PMID: 24825907 Free PMC article.

10

PKCε Is an Essential Mediator of Prostate Cancer Bone Metastasis.

Gutierrez-Uzquiza A, Lopez-Haber C, Jernigan DL, Fatatis A, Kazanietz MG. Gutierrez-Uzquiza A, et al. Mol Cancer Res. 2015 Sep;13(9):1336-46. doi: 10.1158/1541-7786.MCR-15-0111. Epub 2015 May 28. Mol Cancer Res. 2015. PMID: 26023164 Free PMC article.

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