Lorenzo LÉ - Search Results

1

Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia.

Dong W, Jin SC, Allocco A, Zeng X, Sheth AH, Panchagnula S, Castonguay A, Lorenzo LÉ, Islam B, Brindle G, Bachand K, Hu J, Sularz A, Gaillard J, Choi J, Dunbar A, Nelson-Williams C, Kiziltug E, Furey CG, Conine S, Duy PQ, Kundishora AJ, Loring E, Li B, Lu Q, Zhou G, Liu W, Li X, Sierant MC, Mane S, Castaldi C, López-Giráldez F, Knight JR, Sekula RF Jr, Simard JM, Eskandar EN, Gottschalk C, Moliterno J, Günel M, Gerrard JL, Dib-Hajj S, Waxman SG, Barker FG 2nd, Alper SL, Chahine M, Haider S, De Koninck Y, Lifton RP, Kahle KT. Dong W, et al. Among authors: lorenzo le. iScience. 2020 Sep 11;23(10):101552. doi: 10.1016/j.isci.2020.101552. eCollection 2020 Oct 23. iScience. 2020. PMID: 33083721 Free PMC article.

2

Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn.

Labrakakis C, Lorenzo LE, Bories C, Ribeiro-da-Silva A, De Koninck Y. Labrakakis C, et al. Among authors: lorenzo le. Mol Pain. 2009 May 12;5:24. doi: 10.1186/1744-8069-5-24. Mol Pain. 2009. PMID: 19432997 Free PMC article.

3

α5GABA_A Receptors Mediate Tonic Inhibition in the Spinal Cord Dorsal Horn and Contribute to the Resolution Of Hyperalgesia.

Perez-Sanchez J, Lorenzo LE, Lecker I, Zurek AA, Labrakakis C, Bridgwater EM, Orser BA, De Koninck Y, Bonin RP. Perez-Sanchez J, et al. Among authors: lorenzo le. J Neurosci Res. 2017 Jun;95(6):1307-1318. doi: 10.1002/jnr.23981. Epub 2016 Oct 28. J Neurosci Res. 2017. PMID: 27792253

4

Enhancing KCC2 function counteracts morphine-induced hyperalgesia.

Ferrini F, Lorenzo LE, Godin AG, Quang ML, De Koninck Y. Ferrini F, et al. Among authors: lorenzo le. Sci Rep. 2017 Jun 20;7(1):3870. doi: 10.1038/s41598-017-04209-3. Sci Rep. 2017. PMID: 28634406 Free PMC article.

5

Spinal microglia are required for long-term maintenance of neuropathic pain.

Echeverry S, Shi XQ, Yang M, Huang H, Wu Y, Lorenzo LE, Perez-Sanchez J, Bonin RP, De Koninck Y, Zhang J. Echeverry S, et al. Among authors: lorenzo le. Pain. 2017 Sep;158(9):1792-1801. doi: 10.1097/j.pain.0000000000000982. Pain. 2017. PMID: 28746078

6

Reply to The small molecule CLP257 does not modify activity of the K⁺-Cl^- co-transporter KCC2 but does potentiate GABA_A receptor activity.

Gagnon M, Bergeron MJ, Perez-Sanchez J, Plasencia-Fernández I, Lorenzo LE, Godin AG, Castonguay A, Bonin RP, De Koninck Y. Gagnon M, et al. Among authors: lorenzo le. Nat Med. 2017 Dec 7;23(12):1396-1398. doi: 10.1038/nm.4449. Nat Med. 2017. PMID: 29216044 No abstract available.

7

Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing.

Dedek A, Xu J, Kandegedara CM, Lorenzo LÉ, Godin AG, De Koninck Y, Lombroso PJ, Tsai EC, Hildebrand ME. Dedek A, et al. Among authors: lorenzo le. Brain. 2019 Jun 1;142(6):1535-1546. doi: 10.1093/brain/awz105. Brain. 2019. PMID: 31135041 Free PMC article.

8

Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.

Richner M, Pallesen LT, Ulrichsen M, Poulsen ET, Holm TH, Login H, Castonguay A, Lorenzo LE, Gonçalves NP, Andersen OM, Lykke-Hartmann K, Enghild JJ, Rønn LCB, Malik IJ, De Koninck Y, Bjerrum OJ, Vægter CB, Nykjær A. Richner M, et al. Among authors: lorenzo le. Sci Adv. 2019 Jun 19;5(6):eaav9946. doi: 10.1126/sciadv.aav9946. eCollection 2019 Jun. Sci Adv. 2019. PMID: 31223654 Free PMC article.

9

Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes.

Mapplebeck JCS, Lorenzo LE, Lee KY, Gauthier C, Muley MM, De Koninck Y, Prescott SA, Salter MW. Mapplebeck JCS, et al. Among authors: lorenzo le. Cell Rep. 2019 Jul 16;28(3):590-596.e4. doi: 10.1016/j.celrep.2019.06.059. Cell Rep. 2019. PMID: 31315039 Free article.

10

Enhancing neuronal chloride extrusion rescues α2/α3 GABA_A-mediated analgesia in neuropathic pain.

Lorenzo LE, Godin AG, Ferrini F, Bachand K, Plasencia-Fernandez I, Labrecque S, Girard AA, Boudreau D, Kianicka I, Gagnon M, Doyon N, Ribeiro-da-Silva A, De Koninck Y. Lorenzo LE, et al. Nat Commun. 2020 Feb 13;11(1):869. doi: 10.1038/s41467-019-14154-6. Nat Commun. 2020. PMID: 32054836 Free PMC article.

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