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EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance.
Nat Cancer. 2023 Jun;4(6):872-892. doi: 10.1038/s43018-023-00553-8. Epub 2023 May 4.
Nat Cancer. 2023.
PMID: 37142692
Free PMC article.
Senescence and the tumor-immune landscape: Implications for cancer immunotherapy.
Chibaya L, Snyder J, Ruscetti M.
Chibaya L, et al.
Semin Cancer Biol. 2022 Nov;86(Pt 3):827-845. doi: 10.1016/j.semcancer.2022.02.005. Epub 2022 Feb 7.
Semin Cancer Biol. 2022.
PMID: 35143990
Free PMC article.
Review.
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Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.
Chibaya L, Karim B, Zhang H, Jones SN.
Chibaya L, et al.
Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2003193118. doi: 10.1073/pnas.2003193118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33468664
Free PMC article.
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Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer.
Chibaya L, Lusi CF, DeMarco KD, Kane GI, Brassil ML, Parikh CN, Murphy KC, Li J, Naylor TE, Cerrutti J, Peura J, Pitarresi JR, Zhu LJ, Fitzgerald KA, Atukorale PU, Ruscetti M.
Chibaya L, et al.
bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.558307. doi: 10.1101/2023.09.18.558307.
bioRxiv. 2023.
PMID: 37790484
Free PMC article.
Preprint.
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