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Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González R, Conrad T, Stöber MC, Xu R, Giurgiu M, Rodriguez-Fos E, Kasack K, Brückner L, van Leen E, Helmsauer K, Dorado Garcia H, Stefanova ME, Hung KL, Bei Y, Schmelz K, Lodrini M, Mundlos S, Chang HY, Deubzer HE, Sauer S, Eggert A, Schulte JH, Schwarz RF, Haase K, Koche RP, Henssen AG. Chamorro González R, et al. Among authors: bruckner l. Nat Genet. 2023 May;55(5):880-890. doi: 10.1038/s41588-023-01386-y. Epub 2023 May 4. Nat Genet. 2023. PMID: 37142849 Free PMC article.
Coordinated inheritance of extrachromosomal DNA species in human cancer cells.
Hung KL, Jones MG, Wong IT, Lange JT, Luebeck J, Scanu E, He BJ, Brückner L, Li R, González RC, Schmargon R, Dörr JR, Belk JA, Bafna V, Werner B, Huang W, Henssen AG, Mischel PS, Chang HY. Hung KL, et al. Among authors: bruckner l. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549597. doi: 10.1101/2023.07.18.549597. bioRxiv. 2023. PMID: 37503111 Free PMC article. Preprint.
Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer.
Bei Y, Bramé L, Kirchner M, Fritsche-Guenther R, Kunz S, Bhattacharya A, Rusu MC, Gürgen D, Dubios FPB, Köppke JKC, Proba J, Wittstruck N, Sidorova OA, Chamorro González R, Dorado Garcia H, Brückner L, Xu R, Giurgiu M, Rodriguez-Fos E, Yu Q, Spanjaard B, Koche RP, Schmitt CA, Schulte JH, Eggert A, Haase K, Kirwan J, Hagemann AIH, Mertins P, Dörr JR, Henssen AG. Bei Y, et al. Among authors: bruckner l. Cancer Discov. 2024 Mar 1;14(3):492-507. doi: 10.1158/2159-8290.CD-23-1189. Cancer Discov. 2024. PMID: 38197697 Free PMC article.
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models.
Pusch FF, Dorado García H, Xu R, Gürgen D, Bei Y, Brückner L, Röefzaad C, von Stebut J, Bardinet V, Chamorro Gonzalez R, Eggert A, Schulte JH, Hundsdörfer P, Seifert G, Haase K, Schäfer BW, Wachtel M, Kühl AA, Ortiz MV, Wengner AM, Scheer M, Henssen AG. Pusch FF, et al. Among authors: bruckner l. Mol Cancer Ther. 2024 Apr 2;23(4):507-519. doi: 10.1158/1535-7163.MCT-23-0094. Mol Cancer Ther. 2024. PMID: 38159110 Free PMC article.