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Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells.
Sagar S, Rathinavel AK, Lutz WE, Struble LR, Khurana S, Schnaubelt AT, Mishra NK, Guda C, Broadhurst MJ, Reid SPM, Bayles KW, Borgstahl GEO, Radhakrishnan P. Sagar S, et al. Among authors: struble lr. bioRxiv [Preprint]. 2020 Sep 16:2020.09.16.297366. doi: 10.1101/2020.09.16.297366. bioRxiv. 2020. PMID: 32995771 Free PMC article. Updated. Preprint.
BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X. Huang K, et al. Among authors: struble l. Cell Res. 2019 Nov;29(11):942-952. doi: 10.1038/s41422-019-0231-y. Epub 2019 Sep 24. Cell Res. 2019. PMID: 31551537 Free PMC article.
Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.
Sagar S, Rathinavel AK, Lutz WE, Struble LR, Khurana S, Schnaubelt AT, Mishra NK, Guda C, Palermo NY, Broadhurst MJ, Hoffmann T, Bayles KW, Reid SPM, Borgstahl GEO, Radhakrishnan P. Sagar S, et al. Among authors: struble lr. Clin Transl Med. 2021 Feb;11(2):e281. doi: 10.1002/ctm2.281. Clin Transl Med. 2021. PMID: 33635001 Free PMC article. No abstract available.
The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis.
Azadmanesh J, Seleem MA, Struble L, Wood NA, Fisher DJ, Lovelace JJ, Artigues A, Fenton AW, Borgstahl GEO, Ouellette SP, Conda-Sheridan M. Azadmanesh J, et al. Among authors: struble l. J Biol Chem. 2023 Jan;299(1):102762. doi: 10.1016/j.jbc.2022.102762. Epub 2022 Dec 1. J Biol Chem. 2023. PMID: 36463962 Free PMC article.
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