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A novel Sporothrix brasiliensis genomic variant in Midwestern Brazil: evidence for an older and wider sporotrichosis epidemic.
Eudes Filho J, Santos IBD, Reis CMS, Patané JSL, Paredes V, Bernardes JPRA, Poggiani SDSC, Castro TCB, Gomez OM, Pereira SA, Schubach EYP, Gomes KP, Mavengere H, Alves LGB, Lucas J, Paes HC, Albuquerque P, Cruz LM, McEwen JG, Stajich JE, Almeida-Paes R, Zancopé-Oliveira RM, Matute DR, Barker BM, Felipe MSS, Teixeira MM, Nicola AM. Eudes Filho J, et al. Among authors: lucas j. Emerg Microbes Infect. 2020 Dec;9(1):2515-2525. doi: 10.1080/22221751.2020.1847001. Emerg Microbes Infect. 2020. PMID: 33155518 Free PMC article.
Faster Cryptococcus Melanization Increases Virulence in Experimental and Human Cryptococcosis.
de Sousa HR, de Oliveira GP Jr, Frazão SO, Gorgonha KCM, Rosa CP, Garcez EM, Lucas J Jr, Correia AF, de Freitas WF, Borges HM, Brito Alves LG, Paes HC, Trilles L, Lazera MDS, Teixeira MM, Pinto VL Jr, Felipe MSS, Casadevall A, Silva-Pereira I, Albuquerque P, Nicola AM. de Sousa HR, et al. Among authors: lucas j jr. J Fungi (Basel). 2022 Apr 12;8(4):393. doi: 10.3390/jof8040393. J Fungi (Basel). 2022. PMID: 35448624 Free PMC article.
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ.
Li X, Hernandez I, Koyuncu S, Kis B, Häggblad M, Lidemalm L, Abbas AA, Bendegúz S, Göblös A, Brautigam L, Lucas JJ, Carreras-Puigvert J, Hühn D, Pircs K, Vilchez D, Fernandez-Capetillo O. Li X, et al. Among authors: lucas jj. EBioMedicine. 2024 May 2;103:105124. doi: 10.1016/j.ebiom.2024.105124. Online ahead of print. EBioMedicine. 2024. PMID: 38701619
Phased nanopore assembly with Shasta and modular graph phasing with GFAse.
Lorig-Roach R, Meredith M, Monlong J, Jain M, Olsen HE, McNulty B, Porubsky D, Montague TG, Lucas JK, Condon C, Eizenga JM, Juul S, McKenzie SK, Simmonds SE, Park J, Asri M, Koren S, Eichler EE, Axel R, Martin B, Carnevali P, Miga KH, Paten B. Lorig-Roach R, et al. Among authors: lucas jk. Genome Res. 2024 Apr 25;34(3):454-468. doi: 10.1101/gr.278268.123. Genome Res. 2024. PMID: 38627094
Combined approaches, including long-read sequencing, address the diagnostic challenge of HYDIN in primary ciliary dyskinesia.
Fleming A, Galey M, Briggs L, Edwards M, Hogg C, John S, Wilkinson S, Quinn E, Rai R, Burgoyne T, Rogers A, Patel MP, Griffin P, Muller S, Carr SB, Loebinger MR, Lucas JS, Shah A, Jose R, Mitchison HM, Shoemark A, Miller DE, Morris-Rosendahl DJ. Fleming A, et al. Among authors: lucas js. Eur J Hum Genet. 2024 Apr 11. doi: 10.1038/s41431-024-01599-7. Online ahead of print. Eur J Hum Genet. 2024. PMID: 38605126
The variation and evolution of complete human centromeres.
Logsdon GA, Rozanski AN, Ryabov F, Potapova T, Shepelev VA, Catacchio CR, Porubsky D, Mao Y, Yoo D, Rautiainen M, Koren S, Nurk S, Lucas JK, Hoekzema K, Munson KM, Gerton JL, Phillippy AM, Ventura M, Alexandrov IA, Eichler EE. Logsdon GA, et al. Among authors: lucas jk. Nature. 2024 May;629(8010):136-145. doi: 10.1038/s41586-024-07278-3. Epub 2024 Apr 3. Nature. 2024. PMID: 38570684
Gapless assembly of complete human and plant chromosomes using only nanopore sequencing.
Koren S, Bao Z, Guarracino A, Ou S, Goodwin S, Jenike KM, Lucas J, McNulty B, Park J, Rautiainen M, Rhie A, Roelofs D, Schneiders H, Vrijenhoek I, Nijbroek K, Ware D, Schatz MC, Garrison E, Huang S, McCombie WR, Miga KH, Wittenberg AHJ, Phillippy AM. Koren S, et al. Among authors: lucas j. bioRxiv [Preprint]. 2024 Mar 19:2024.03.15.585294. doi: 10.1101/2024.03.15.585294. bioRxiv. 2024. PMID: 38529488 Free PMC article. Preprint.
2,366 results