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Year Number of Results
2018 1
2019 2
2020 3
2021 3
2023 2
2024 0

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11 results

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Page 1
An aged immune system drives senescence and ageing of solid organs.
Yousefzadeh MJ, Flores RR, Zhu Y, Schmiechen ZC, Brooks RW, Trussoni CE, Cui Y, Angelini L, Lee KA, McGowan SJ, Burrack AL, Wang D, Dong Q, Lu A, Sano T, O'Kelly RD, McGuckian CA, Kato JI, Bank MP, Wade EA, Pillai SPS, Klug J, Ladiges WC, Burd CE, Lewis SE, LaRusso NF, Vo NV, Wang Y, Kelley EE, Huard J, Stromnes IM, Robbins PD, Niedernhofer LJ. Yousefzadeh MJ, et al. Among authors: angelini l. Nature. 2021 Jun;594(7861):100-105. doi: 10.1038/s41586-021-03547-7. Epub 2021 May 12. Nature. 2021. PMID: 33981041 Free PMC article.
Fisetin is a senotherapeutic that extends health and lifespan.
Yousefzadeh MJ, Zhu Y, McGowan SJ, Angelini L, Fuhrmann-Stroissnigg H, Xu M, Ling YY, Melos KI, Pirtskhalava T, Inman CL, McGuckian C, Wade EA, Kato JI, Grassi D, Wentworth M, Burd CE, Arriaga EA, Ladiges WL, Tchkonia T, Kirkland JL, Robbins PD, Niedernhofer LJ. Yousefzadeh MJ, et al. Among authors: angelini l. EBioMedicine. 2018 Oct;36:18-28. doi: 10.1016/j.ebiom.2018.09.015. Epub 2018 Sep 29. EBioMedicine. 2018. PMID: 30279143 Free PMC article.
Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.
Dorronsoro A, Santiago FE, Grassi D, Zhang T, Lai RC, McGowan SJ, Angelini L, Lavasani M, Corbo L, Lu A, Brooks RW, Garcia-Contreras M, Stolz DB, Amelio A, Boregowda SV, Fallahi M, Reich A, Ricordi C, Phinney DG, Huard J, Lim SK, Niedernhofer LJ, Robbins PD. Dorronsoro A, et al. Among authors: angelini l. Aging Cell. 2021 Apr;20(4):e13337. doi: 10.1111/acel.13337. Epub 2021 Mar 16. Aging Cell. 2021. PMID: 33728821 Free PMC article.
Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.
Henpita C, Vyas R, Healy CL, Kieu TL, Gurkar AU, Yousefzadeh MJ, Cui Y, Lu A, Angelini LA, O'Kelly RD, McGowan SJ, Chandrasekhar S, Vanderpool RR, Hennessy-Wack D, Ross MA, Bachman TN, McTiernan C, Pillai SPS, Ladiges W, Lavasani M, Huard J, Beer-Stolz D, St Croix CM, Watkins SC, Robbins PD, Mora AL, Kelley EE, Wang Y, O'Connell TD, Niedernhofer LJ. Henpita C, et al. Among authors: angelini la. Aging Cell. 2023 Apr;22(4):e13782. doi: 10.1111/acel.13782. Epub 2023 Feb 3. Aging Cell. 2023. PMID: 36734200 Free PMC article.
Mouse Models of Accelerated Cellular Senescence.
Yousefzadeh MJ, Melos KI, Angelini L, Burd CE, Robbins PD, Niedernhofer LJ. Yousefzadeh MJ, et al. Among authors: angelini l. Methods Mol Biol. 2019;1896:203-230. doi: 10.1007/978-1-4939-8931-7_17. Methods Mol Biol. 2019. PMID: 30474850 Free PMC article.
Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice.
Flores RR, Carbo L, Kim E, Van Meter M, De Padilla CML, Zhao J, Colangelo D, Yousefzadeh MJ, Angelini LA, Zhang L, Pola E, Vo N, Evans CH, Gambotto A, Niedernhofer LJ, Robbins PD. Flores RR, et al. Among authors: angelini la. FASEB J. 2019 Aug;33(8):9505-9515. doi: 10.1096/fj.201900420R. Epub 2019 Jun 6. FASEB J. 2019. PMID: 31170010 Free PMC article.
Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice.
Yousefzadeh MJ, Huerta Guevara AP, Postmus AC, Flores RR, Sano T, Jurdzinski A, Angelini L, McGowan SJ, O'Kelly RD, Wade EA, Gonzalez-Espada LV, Henessy-Wack D, Howard S, Rozgaja TA, Trussoni CE, LaRusso NF, Eggen BJL, Jonker JW, Robbins PD, Niedernhofer LJ, Kruit JK. Yousefzadeh MJ, et al. Among authors: angelini l. Aging Biol. 2023;1(1):20230015. doi: 10.59368/agingbio.20230015. Epub 2023 Oct 23. Aging Biol. 2023. PMID: 38124711 Free PMC article.
ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging.
Zhao J, Zhang L, Lu A, Han Y, Colangelo D, Bukata C, Scibetta A, Yousefzadeh MJ, Li X, Gurkar AU, McGowan SJ, Angelini L, O'Kelly R, Li H, Corbo L, Sano T, Nick H, Pola E, Pilla SPS, Ladiges WC, Vo N, Huard J, Niedernhofer LJ, Robbins PD. Zhao J, et al. Among authors: angelini l. Aging (Albany NY). 2020 Mar 22;12(6):4688-4710. doi: 10.18632/aging.102863. Epub 2020 Mar 22. Aging (Albany NY). 2020. PMID: 32201398 Free PMC article.
Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging.
Zhang L, Zhao J, Mu X, McGowan SJ, Angelini L, O'Kelly RD, Yousefzadeh MJ, Sakamoto A, Aversa Z, LeBrasseur NK, Suh Y, Huard J, Kamenecka TM, Niedernhofer LJ, Robbins PD. Zhang L, et al. Among authors: angelini l. Aging Cell. 2021 Dec;20(12):e13486. doi: 10.1111/acel.13486. Epub 2021 Nov 3. Aging Cell. 2021. PMID: 34734460 Free PMC article.
11 results