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Prehospital use of magnesium sulfate as neuroprotection in acute stroke.
Saver JL, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N; FAST-MAG Investigators and Coordinators. Saver JL, et al. N Engl J Med. 2015 Feb 5;372(6):528-36. doi: 10.1056/NEJMoa1408827. N Engl J Med. 2015. PMID: 25651247 Free PMC article. Clinical Trial.
A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke.
Lyden PD, Diniz MA, Bosetti F, Lamb J, Nagarkatti KA, Rogatko A, Kim S, Cabeen RP, Koenig JI, Akhter K, Arbab AS, Avery BD, Beatty HE, Bibic A, Cao S, Simoes Braga Boisserand L, Chamorro A, Chauhan A, Diaz-Perez S, Dhandapani K, Dhanesha N, Goh A, Herman AL, Hyder F, Imai T, Johnson CW, Khan MB, Kamat P, Karuppagounder SS, Kumskova M, Mihailovic JM, Mandeville JB, Morais A, Patel RB, Sanganahalli BG, Smith C, Shi Y, Sutariya B, Thedens D, Qin T, Velazquez SE, Aronowski J, Ayata C, Chauhan AK, Leira EC, Hess DC, Koehler RC, McCullough LD, Sansing LH. Lyden PD, et al. Sci Transl Med. 2023 Sep 20;15(714):eadg8656. doi: 10.1126/scitranslmed.adg8656. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37729432 Clinical Trial.
The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results.
Lyden PD, Bosetti F, Diniz MA, Rogatko A, Koenig JI, Lamb J, Nagarkatti KA, Cabeen RP, Hess DC, Kamat PK, Khan MB, Wood K, Dhandapani K, Arbab AS, Leira EC, Chauhan AK, Dhanesha N, Patel RB, Kumskova M, Thedens D, Morais A, Imai T, Qin T, Ayata C, Boisserand LSB, Herman AL, Beatty HE, Velazquez SE, Diaz-Perez S, Sanganahalli BG, Mihailovic JM, Hyder F, Sansing LH, Koehler RC, Lannon S, Shi Y, Karuppagounder SS, Bibic A, Akhter K, Aronowski J, McCullough LD, Chauhan A, Goh A; SPAN Investigators. Lyden PD, et al. Stroke. 2022 May;53(5):1802-1812. doi: 10.1161/STROKEAHA.121.038047. Epub 2022 Mar 31. Stroke. 2022. PMID: 35354299 Free PMC article. Clinical Trial.
PHLPP1 gene deletion protects the brain from ischemic injury.
Chen B, Van Winkle JA, Lyden PD, Brown JH, Purcell NH. Chen B, et al. Among authors: lyden pd. J Cereb Blood Flow Metab. 2013 Feb;33(2):196-204. doi: 10.1038/jcbfm.2012.150. Epub 2012 Oct 17. J Cereb Blood Flow Metab. 2013. PMID: 23072745 Free PMC article.
234 results