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1985 1
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13 results

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Page 1
The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium.
Jimenez MT, Clark ML, Wright JM, Michieletto MF, Liu S, Erickson I, Dohnalova L, Uhr GT, Tello-Cajiao J, Joannas L, Williams A, Gagliani N, Bewtra M, Tomov VT, Thaiss CA, Henao-Mejia J. Jimenez MT, et al. Among authors: bewtra m. J Exp Med. 2022 Dec 5;219(12):e20212278. doi: 10.1084/jem.20212278. Epub 2022 Sep 8. J Exp Med. 2022. PMID: 36074090 Free PMC article.
Increased Mortality Rates With Prolonged Corticosteroid Therapy When Compared With Antitumor Necrosis Factor-α-Directed Therapy for Inflammatory Bowel Disease.
Lewis JD, Scott FI, Brensinger CM, Roy JA, Osterman MT, Mamtani R, Bewtra M, Chen L, Yun H, Xie F, Curtis JR. Lewis JD, et al. Among authors: bewtra m. Am J Gastroenterol. 2018 Mar;113(3):405-417. doi: 10.1038/ajg.2017.479. Epub 2018 Jan 16. Am J Gastroenterol. 2018. PMID: 29336432 Free PMC article.
C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks--final results of the I.M.P.A.C.T.2 study.
Craig TJ, Bewtra AK, Bahna SL, Hurewitz D, Schneider LC, Levy RJ, Moy JN, Offenberger J, Jacobson KW, Yang WH, Eidelman F, Janss G, Packer FR, Rojavin MA, Machnig T, Keinecke HO, Wasserman RL. Craig TJ, et al. Among authors: bewtra ak. Allergy. 2011 Dec;66(12):1604-11. doi: 10.1111/j.1398-9995.2011.02702.x. Epub 2011 Sep 2. Allergy. 2011. PMID: 21884533 Clinical Trial.
BACKGROUND: The placebo-controlled study International Multicentre Prospective Angioedema C1-INH Trial 1 (I.M.P.A.C.T.1) demonstrated that 20 U/kg C1 esterase inhibitor (C1-INH) concentrate (Berinert; CSL Behring, Marburg, Germany) is effective in treating acute abdominal …
BACKGROUND: The placebo-controlled study International Multicentre Prospective Angioedema C1-INH Trial 1 (I.M.P.A.C.T.1) demonstrated …
Treatment response after repeated administration of C1 esterase inhibitor for successive acute hereditary angioedema attacks.
Craig TJ, Bewtra AK, Hurewitz D, Levy R, Janss G, Jacobson KW, Packer F, Bernstein JA, Rojavin MA, Machnig T, Keinecke HO, Wasserman RL. Craig TJ, et al. Among authors: bewtra ak. Allergy Asthma Proc. 2012 Jul-Aug;33(4):354-61. doi: 10.2500/aap.2012.33.3589. Allergy Asthma Proc. 2012. PMID: 22856636 Clinical Trial.
In a post hoc analysis of an open-label extension study (International Multicenter Prospective Angioedema C1-INH Trial [I.M.P.A.C.T.2]), the association between repeated treatment with C1-INH and times to onset of symptom relief and complete resolution of HAE symptoms was …
In a post hoc analysis of an open-label extension study (International Multicenter Prospective Angioedema C1-INH Trial [I.M.P.A.C.T.2 …
IL-1 receptor-type expression in relation to atopy.
Gupta K, Bewtra A. Gupta K, et al. Among authors: bewtra a. J Allergy Clin Immunol. 1999 Jun;103(6):1100-7. doi: 10.1016/s0091-6749(99)70185-5. J Allergy Clin Immunol. 1999. PMID: 10359892
BACKGROUND: IL-1 has 2 receptors, type I (IL-1RI) and type II (IL-1RII), which have 2 forms each, membrane (m) and soluble (s). When IL-1 binds to mIL-1RI, the active receptor, an inflammatory response is initiated, which does not occur when IL-1 binds to mIL-1RII, the dec …
BACKGROUND: IL-1 has 2 receptors, type I (IL-1RI) and type II (IL-1RII), which have 2 forms each, membrane (m) and soluble (s). When …
Effect of cetirizine on human eosinophil superoxide generation, eosinophil chemotaxis and eosinophil peroxidase in vitro.
Okada C, Eda R, Miyagawa H, Sugiyama H, Hopp RJ, Bewtra AK, Townley RG. Okada C, et al. Among authors: bewtra ak. Int Arch Allergy Immunol. 1994;103(4):384-90. doi: 10.1159/000236658. Int Arch Allergy Immunol. 1994. PMID: 8130652
In allergic subjects, superoxide anion generation 60 min after platelet-activating factor (PAF) activation was inhibited by concentrations of cetirizine ranging from 0.01 to 1 microgram/ml (2.612 x 10(-8) to 2.612 x 10(-6) M). No significant inhibition was observed in norm …
In allergic subjects, superoxide anion generation 60 min after platelet-activating factor (PAF) activation was inhibited by concentrations o …
Inactivation of horseradish peroxidase by phenol and hydrogen peroxide: a kinetic investigation.
Baynton KJ, Bewtra JK, Biswas N, Taylor KE. Baynton KJ, et al. Among authors: bewtra jk. Biochim Biophys Acta. 1994 Jun 12;1206(2):272-8. doi: 10.1016/0167-4838(94)90218-6. Biochim Biophys Acta. 1994. PMID: 8003531
The overall inactivation comprised of both processes exhibits a second-order inactivation rate constant (kapp) of 0.023 +/- 0.005 M-1 s-1 at pH 7.4 and 25 degrees C. In the presence of both hydrogen peroxide fixed at 0.5 mM and phenol, HRP was inactivated in an irreversibl …
The overall inactivation comprised of both processes exhibits a second-order inactivation rate constant (kapp) of 0.023 +/- 0.005 M-1 …
Density distribution and density conversion of neutrophils in allergic subjects.
Miyagawa H, Okada C, Sugiyama H, Hopp RJ, Agrawal DK, Nabe M, Gordy C, Bewtra AK, Townley RG. Miyagawa H, et al. Among authors: bewtra ak. Int Arch Allergy Appl Immunol. 1990;93(1):8-13. doi: 10.1159/000235272. Int Arch Allergy Appl Immunol. 1990. PMID: 2086489
In neutrophils from AR subjects (fraction 3), chemotaxis to N-formyl-methionyl-leucyl-phenylalanine or platelet-activating factor (PAF) was enhanced compared to fraction 2. PAF (10(-7) M) changed the density of neutrophils (p less than 0.01), which were inhibited by WEB 20 …
In neutrophils from AR subjects (fraction 3), chemotaxis to N-formyl-methionyl-leucyl-phenylalanine or platelet-activating factor (PAF) was …
Effect of formoterol on superoxide anion generation from bronchoalveolar lavage cells after antigen challenge in guinea pigs.
Okada C, Sugiyama H, Eda R, Miyagawa H, Hopp RJ, Bewtra AK, Townley RG. Okada C, et al. Among authors: bewtra ak. Am J Respir Cell Mol Biol. 1993 May;8(5):509-17. doi: 10.1165/ajrcmb/8.5.509. Am J Respir Cell Mol Biol. 1993. PMID: 8386928
Antigen challenge enhanced superoxide anion generation from eosinophils, from 5.39 +/- 1.08 to 13.19 +/- 1.95 nmol 60 min after phorbol myristate acetate (PMA) (1 ng/ml) activation, and 0.22 +/- 0.49 to 3.34 +/- 1.67 nmol 40 min after platelet-activating factor (PAF) (10(-6) M …
Antigen challenge enhanced superoxide anion generation from eosinophils, from 5.39 +/- 1.08 to 13.19 +/- 1.95 nmol 60 min after phorbol myri …
13 results