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Year Number of Results
1984 2
1985 3
1986 1
1987 1
1988 2
1989 3
1990 3
1991 6
1992 8
1993 9
1994 13
1995 8
1996 13
1997 16
1998 18
1999 24
2000 27
2001 33
2002 40
2003 54
2004 46
2005 80
2006 79
2007 98
2008 114
2009 137
2010 142
2011 166
2012 202
2013 231
2014 328
2015 362
2016 387
2017 396
2018 478
2019 585
2020 693
2021 779
2022 920
2023 932
2024 431

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6,962 results

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Page 1
Lactylation-driven METTL3-mediated RNA m(6)A modification promotes immunosuppression of tumor-infiltrating myeloid cells.
Xiong J, He J, Zhu J, Pan J, Liao W, Ye H, Wang H, Song Y, Du Y, Cui B, Xue M, Zheng W, Kong X, Jiang K, Ding K, Lai L, Wang Q. Xiong J, et al. Among authors: ding k. Mol Cell. 2022 May 5;82(9):1660-1677.e10. doi: 10.1016/j.molcel.2022.02.033. Epub 2022 Mar 22. Mol Cell. 2022. PMID: 35320754 Free article.
Our study revealed that the increased expression of methyltransferase-like 3 (METTL3) in TIMs was correlated with the poor prognosis of colon cancer patients, and myeloid deficiency of METTL3 attenuated tumor growth in mice. METTL3 mediated m(6)A modification on Jak1 mRNA …
Our study revealed that the increased expression of methyltransferase-like 3 (METTL3) in TIMs was correlated with the poor prognosis of colo …
Epigenetic Modifications of mRNA and DNA in Plants.
Liang Z, Riaz A, Chachar S, Ding Y, Du H, Gu X. Liang Z, et al. Among authors: ding y. Mol Plant. 2020 Jan 6;13(1):14-30. doi: 10.1016/j.molp.2019.12.007. Epub 2019 Dec 18. Mol Plant. 2020. PMID: 31863849 Free article. Review.
Advances in the detection and mapping of messenger RNA (mRNA) N(6)-methyladenosine (m(6)A) and 5-methylcytosine (m(5)C), and DNA N(6)-methyldeoxyadenosine (6mA) redefined our understanding of these modifications as additional tiers of epigenetic regulation. In plant …
Advances in the detection and mapping of messenger RNA (mRNA) N(6)-methyladenosine (m(6)A) and 5-methylcytosine (m(5)C), and D …
m(6)A modulates haematopoietic stem and progenitor cell specification.
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F. Zhang C, et al. Among authors: ding y. Nature. 2017 Sep 14;549(7671):273-276. doi: 10.1038/nature23883. Epub 2017 Sep 6. Nature. 2017. PMID: 28869969
Although the rapid development of high-throughput sequencing technologies has enabled insight into the biological functions of m(6)A modification, the function of m(6)A during vertebrate embryogenesis remains poorly understood. Here we show that m(6)A determi …
Although the rapid development of high-throughput sequencing technologies has enabled insight into the biological functions of m(6)A …
m(6) A-Dependent Modulation via IGF2BP3/MCM5/Notch Axis Promotes Partial EMT and LUAD Metastasis.
Yang X, Bai Q, Chen W, Liang J, Wang F, Gu W, Liu L, Li Q, Chen Z, Zhou A, Long J, Tian H, Wu J, Ding X, Zhou N, Li M, Yang Y, Cai J. Yang X, et al. Among authors: ding x. Adv Sci (Weinh). 2023 Jul;10(20):e2206744. doi: 10.1002/advs.202206744. Epub 2023 May 12. Adv Sci (Weinh). 2023. PMID: 37171793 Free PMC article.
The importance of mRNA N6-methyladenosine (m(6) A) modification during tumor metastasis is controversial as it plays distinct roles in different biological contexts. Moreover, how cancer cell plasticity is shaped by m(6) A modification is interesting but remains unc …
The importance of mRNA N6-methyladenosine (m(6) A) modification during tumor metastasis is controversial as it plays distinct roles i …
YTHDF1 Regulates Pulmonary Hypertension through Translational Control of MAGED1.
Hu L, Wang J, Huang H, Yu Y, Ding J, Yu Y, Li K, Wei D, Ye Q, Wang F, Shen B, Chen J, Fulton DJR, Chen F. Hu L, et al. Among authors: ding j. Am J Respir Crit Care Med. 2021 May 1;203(9):1158-1172. doi: 10.1164/rccm.202009-3419OC. Am J Respir Crit Care Med. 2021. PMID: 33465322
Whether m(6)A RNA modification and m(6)A effector proteins play a role in pulmonary vascular remodeling and PH has not been demonstrated.Objectives: To determine whether m(6)A modification and m(6)A effectors contribute to the pathogenesis of PH.Method …
Whether m(6)A RNA modification and m(6)A effector proteins play a role in pulmonary vascular remodeling and PH has not been de …
m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
Chen Y, Wang J, Xu D, Xiang Z, Ding J, Yang X, Li D, Han X. Chen Y, et al. Among authors: ding j. Autophagy. 2021 Feb;17(2):457-475. doi: 10.1080/15548627.2020.1720431. Epub 2020 Jan 31. Autophagy. 2021. PMID: 31983283 Free PMC article.
These events led to reduced mRNA methylation levels of N(6)-methyladenosine (m(6)A) and enhanced autophagy in LCs. Similar regulation of METTL14, ALKBH5, and m(6)A was also observed in LCs upon treatment with human chorionic gonadotropin (HsCG). ...Thus, m(6) …
These events led to reduced mRNA methylation levels of N(6)-methyladenosine (m(6)A) and enhanced autophagy in LCs. Similar regulation …
Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer.
Ding JH, Xiao Y, Yang F, Song XQ, Xu Y, Ding XH, Ding R, Shao ZM, Di GH, Jiang YZ. Ding JH, et al. Among authors: ding xh, ding r. Sci Transl Med. 2024 Jan 3;16(728):eadg7740. doi: 10.1126/scitranslmed.adg7740. Epub 2024 Jan 3. Sci Transl Med. 2024. PMID: 38170790
Therefore, GDP-M supplementation combined with PARP inhibition augmented the efficacy of anti-PD-1 antibodies. Together, these findings suggest that GDP-M is a crucial HRD-related metabolite and propose a promising therapeutic strategy for TNBCs with low HRD scores …
Therefore, GDP-M supplementation combined with PARP inhibition augmented the efficacy of anti-PD-1 antibodies. Together, these findin …
Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.
Srivastava AK, Wang Y, Huang R, Skinner C, Thompson T, Pollard L, Wood T, Luo F, Stevenson R, Polimanti R, Gelernter J, Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Yap F, Kwek K, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group; Kapoor A, Lee D, Chakravarti A, Maercker C, Graf F, Boutros M, Stamoulis G, Santoni F, Makrythanasis P, Letourneau A, Guipponi M, Panousis N, Garieri M, Ribaux P, Falconnet E, Borel C, Antonarakis SE, Kumar S, Curran J, Blangero J, Chatterjee S, Kapoor A, Akiyama J, Auer D, Berrios C, Pennacchio L, Chakravarti A, Donti TR, Cappuccio G, Miller M, Atwal P, Kennedy A, Cardon A, Bacino C, Emrick L, Hertecant J, Baumer F, Porter B, Bainbridge M, Bonnen P, Graham B, Sutton R, Sun Q, Elsea S, Hu Z, Wang P, Zhu Y, Zhao J, Xiong M, Bennett DA, Hidalgo-Miranda A, Romero-Cordoba S, Rodriguez-Cuevas S, Rebollar-Vega R, Tagliabue E, Iorio M, D’Ippolito E, Baroni S, Kaczkowski B, Tanaka Y, Kawaji H, Sandelin A, Andersson R, Itoh M, Lassmann T; The FANTOM5 Consortium; Hayashizaki Y, Carninci P, Forrest ARR, Semple CA, Rosenthal EA, Shirts B, Amendola L, Gallego C, Horike-Pyne… See abstract for full author list ➔ Srivastava AK, et al. Among authors: ding y. Hum Genomics. 2016 May 26;10 Suppl 1(Suppl 1):12. doi: 10.1186/s40246-016-0063-5. Hum Genomics. 2016. PMID: 27294413 Free PMC article.
M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. ...M. Edrees, M. Athar, F. A. Al-Allaf, M. M. Taher, W. Khan, A. Bouazzaoui, N. ...
M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. ...M. Edrees, M. Athar, F. A. Al …
Reading and writing of mRNA m(6)A modification orchestrate maternal-to-zygotic transition in mice.
Zhu W, Ding Y, Meng J, Gu L, Liu W, Li L, Chen H, Wang Y, Li Z, Li C, Sun Y, Liu Z. Zhu W, et al. Among authors: ding y. Genome Biol. 2023 Apr 6;24(1):67. doi: 10.1186/s13059-023-02918-9. Genome Biol. 2023. PMID: 37024923 Free PMC article.
N(6)-methyladenosine (m(6)A) modification has been shown to regulate RNA metabolism. ...We identify Ythdc1 and Ythdf2 as key m(6)A readers for mouse preimplantation development. Our study reveals a key role of m(6)A mediated RNA metabolism during MZT in mamma …
N(6)-methyladenosine (m(6)A) modification has been shown to regulate RNA metabolism. ...We identify Ythdc1 and Ythdf2 as key m …
Mettl14-mediated m(6)A modification ensures the cell-cycle progression of late-born retinal progenitor cells.
Li L, Sun Y, Davis AE, Shah SH, Hamed LK, Wu MR, Lin CH, Ding JB, Wang S. Li L, et al. Among authors: ding jb. Cell Rep. 2023 Jun 27;42(6):112596. doi: 10.1016/j.celrep.2023.112596. Epub 2023 Jun 1. Cell Rep. 2023. PMID: 37269288 Free PMC article.
Conditional deletion of Mettl14, which is required for depositing m(6)A, led to delayed cell-cycle exit of late-born RPCs but has no effect on retinal development prior to birth. m(6)A sequencing and single-cell transcriptomics revealed that mRNAs involved in elonga …
Conditional deletion of Mettl14, which is required for depositing m(6)A, led to delayed cell-cycle exit of late-born RPCs but has no …
6,962 results