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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1976 1
1978 2
1981 1
1982 1
1983 4
1984 1
1986 1
1987 5
1988 4
1989 2
1990 2
1991 4
1992 2
1993 7
1994 5
1995 5
1996 3
1997 10
1998 10
1999 14
2000 26
2001 21
2002 29
2003 41
2004 25
2005 32
2006 57
2007 60
2008 81
2009 80
2010 85
2011 111
2012 124
2013 153
2014 183
2015 211
2016 220
2017 228
2018 262
2019 342
2020 376
2021 393
2022 461
2023 492
2024 197

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3,901 results

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Page 1
Lactylation-driven METTL3-mediated RNA m(6)A modification promotes immunosuppression of tumor-infiltrating myeloid cells.
Xiong J, He J, Zhu J, Pan J, Liao W, Ye H, Wang H, Song Y, Du Y, Cui B, Xue M, Zheng W, Kong X, Jiang K, Ding K, Lai L, Wang Q. Xiong J, et al. Among authors: kong x. Mol Cell. 2022 May 5;82(9):1660-1677.e10. doi: 10.1016/j.molcel.2022.02.033. Epub 2022 Mar 22. Mol Cell. 2022. PMID: 35320754 Free article.
Our study revealed that the increased expression of methyltransferase-like 3 (METTL3) in TIMs was correlated with the poor prognosis of colon cancer patients, and myeloid deficiency of METTL3 attenuated tumor growth in mice. METTL3 mediated m(6)A modification on Jak1 mRNA …
Our study revealed that the increased expression of methyltransferase-like 3 (METTL3) in TIMs was correlated with the poor prognosis of colo …
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates.
Corbett KS, Flynn B, Foulds KE, Francica JR, Boyoglu-Barnum S, Werner AP, Flach B, O'Connell S, Bock KW, Minai M, Nagata BM, Andersen H, Martinez DR, Noe AT, Douek N, Donaldson MM, Nji NN, Alvarado GS, Edwards DK, Flebbe DR, Lamb E, Doria-Rose NA, Lin BC, Louder MK, O'Dell S, Schmidt SD, Phung E, Chang LA, Yap C, Todd JM, Pessaint L, Van Ry A, Browne S, Greenhouse J, Putman-Taylor T, Strasbaugh A, Campbell TA, Cook A, Dodson A, Steingrebe K, Shi W, Zhang Y, Abiona OM, Wang L, Pegu A, Yang ES, Leung K, Zhou T, Teng IT, Widge A, Gordon I, Novik L, Gillespie RA, Loomis RJ, Moliva JI, Stewart-Jones G, Himansu S, Kong WP, Nason MC, Morabito KM, Ruckwardt TJ, Ledgerwood JE, Gaudinski MR, Kwong PD, Mascola JR, Carfi A, Lewis MG, Baric RS, McDermott A, Moore IN, Sullivan NJ, Roederer M, Seder RA, Graham BS. Corbett KS, et al. Among authors: kong wp. N Engl J Med. 2020 Oct 15;383(16):1544-1555. doi: 10.1056/NEJMoa2024671. Epub 2020 Jul 28. N Engl J Med. 2020. PMID: 32722908 Free PMC article.
The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of STAT1 mRNA.
Liu Y, Liu Z, Tang H, Shen Y, Gong Z, Xie N, Zhang X, Wang W, Kong W, Zhou Y, Fu Y. Liu Y, et al. Among authors: kong w. Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C762-C775. doi: 10.1152/ajpcell.00212.2019. Epub 2019 Jul 31. Am J Physiol Cell Physiol. 2019. PMID: 31365297 Free article.
Compelling evidence indicates that epigenetic regulations orchestrate dynamic macrophage polarization. N(6)-methyladenosine (m(6)A) methylation is the most abundant epigenetic modification of mammalian mRNA, but its role in macrophage polarization is still completely unkno …
Compelling evidence indicates that epigenetic regulations orchestrate dynamic macrophage polarization. N(6)-methyladenosine (m(6)A) m …
Mettl1-mediated internal m(7)G methylation of Sptbn2 mRNA elicits neurogenesis and anti-alzheimer's disease.
Li Q, Liu H, Li L, Guo H, Xie Z, Kong X, Xu J, Zhang J, Chen Y, Zhang Z, Liu J, Xuan A. Li Q, et al. Among authors: kong x. Cell Biosci. 2023 Oct 1;13(1):183. doi: 10.1186/s13578-023-01131-2. Cell Biosci. 2023. PMID: 37779199 Free PMC article.
BACKGROUND: N(7)-methylguanosine (m(7)G) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation. ...Morris water maze was used to detect the cognitive function. METHODS: We found that m(7)G methyltransferase comple …
BACKGROUND: N(7)-methylguanosine (m(7)G) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, a …
Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.
Srivastava AK, Wang Y, Huang R, Skinner C, Thompson T, Pollard L, Wood T, Luo F, Stevenson R, Polimanti R, Gelernter J, Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Yap F, Kwek K, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group; Kapoor A, Lee D, Chakravarti A, Maercker C, Graf F, Boutros M, Stamoulis G, Santoni F, Makrythanasis P, Letourneau A, Guipponi M, Panousis N, Garieri M, Ribaux P, Falconnet E, Borel C, Antonarakis SE, Kumar S, Curran J, Blangero J, Chatterjee S, Kapoor A, Akiyama J, Auer D, Berrios C, Pennacchio L, Chakravarti A, Donti TR, Cappuccio G, Miller M, Atwal P, Kennedy A, Cardon A, Bacino C, Emrick L, Hertecant J, Baumer F, Porter B, Bainbridge M, Bonnen P, Graham B, Sutton R, Sun Q, Elsea S, Hu Z, Wang P, Zhu Y, Zhao J, Xiong M, Bennett DA, Hidalgo-Miranda A, Romero-Cordoba S, Rodriguez-Cuevas S, Rebollar-Vega R, Tagliabue E, Iorio M, D’Ippolito E, Baroni S, Kaczkowski B, Tanaka Y, Kawaji H, Sandelin A, Andersson R, Itoh M, Lassmann T; The FANTOM5 Consortium; Hayashizaki Y, Carninci P, Forrest ARR, Semple CA, Rosenthal EA, Shirts B, Amendola L, Gallego C, Horike-Pyne… See abstract for full author list ➔ Srivastava AK, et al. Among authors: kong y. Hum Genomics. 2016 May 26;10 Suppl 1(Suppl 1):12. doi: 10.1186/s40246-016-0063-5. Hum Genomics. 2016. PMID: 27294413 Free PMC article.
M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. ...M. Edrees, M. Athar, F. A. Al-Allaf, M. M. Taher, W. Khan, A. Bouazzaoui, N. ...
M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. ...M. Edrees, M. Athar, F. A. Al
Smoldering multiple myeloma.
Gao M, Yang G, Kong Y, Wu X, Shi J. Gao M, et al. Among authors: kong y. Biomed Res Int. 2015;2015:623254. doi: 10.1155/2015/623254. Epub 2015 Apr 27. Biomed Res Int. 2015. PMID: 26000300 Free PMC article. Review.
Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM) characterized by clonal bone marrow plasma cells (BMPC) 10% and/or M protein level 30 g/L in the absence of end organ damage. It represents an intermediate stage between monoclona …
Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM) characterized by clonal bone marrow plasma cel …
Novel insight into RNA modifications in tumor immunity: Promising targets to prevent tumor immune escape.
Kong Y, Yu J, Ge S, Fan X. Kong Y, et al. Innovation (Camb). 2023 May 29;4(4):100452. doi: 10.1016/j.xinn.2023.100452. eCollection 2023 Jul 10. Innovation (Camb). 2023. PMID: 37485079 Free PMC article. Review.
Notably, recent clinical trials have shown that epigenetic drugs can significantly improve the outcome of ICI therapy in various cancers, indicating the importance of epigenetic modifications in immune regulation of tumors. Recently, RNA modifications (N(6)-methyladenosine [m
Notably, recent clinical trials have shown that epigenetic drugs can significantly improve the outcome of ICI therapy in various cancers, in …
Heterobimetallic μ2-halocarbyne complexes.
Burt LK, Dewhurst RD, Hill AF, Kong RY, Nahon EE, Onn CS. Burt LK, et al. Among authors: kong ry. Dalton Trans. 2022 Aug 16;51(32):12080-12099. doi: 10.1039/d2dt01558g. Dalton Trans. 2022. PMID: 35895297
The halocarbyne complexes [M(CX)(CO)(2)(Tp*)] (M = Mo, W; X = Cl, Br; Tp* = hydrotris(dimethylpyrazolyl)borate) react with [AuCl(SMe(2))], [Pt(eta(2)-H(2)CCH(2))(PPh(3))(2)] or [Pt(eta(2)-nbe)(3)] (nbe = norbornene) to furnish rare examples of mu(2)-halocarbyne comp …
The halocarbyne complexes [M(CX)(CO)(2)(Tp*)] (M = Mo, W; X = Cl, Br; Tp* = hydrotris(dimethylpyrazolyl)borate) react with [Au …
The landscape of m(1)A modification and its posttranscriptional regulatory functions in primary neurons.
Zhang C, Yi X, Hou M, Li Q, Li X, Lu L, Qi E, Wu M, Qi L, Jian H, Qi Z, Lv Y, Kong X, Bi M, Feng S, Zhou H. Zhang C, et al. Among authors: kong x. Elife. 2023 Mar 7;12:e85324. doi: 10.7554/eLife.85324. Elife. 2023. PMID: 36880874 Free PMC article.
The m(1)A landscape and potential functions of m(1)A modification in neurons remain poorly understood. ...We investigated the m(1)A landscape in primary neurons, identified m(1)A-modified RNAs, and found that OGD/R increased the number of m(1)A …
The m(1)A landscape and potential functions of m(1)A modification in neurons remain poorly understood. ...We investigated the …
3,901 results