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GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study.
Tramutola A, Bakels HS, Perrone F, Di Nottia M, Mazza T, Abruzzese MP, Zoccola M, Pagnotta S, Carrozzo R, de Bot ST, Perluigi M, van Roon-Mom WMC, Squitieri F. Tramutola A, et al. Among authors: perluigi m. EBioMedicine. 2023 Nov;97:104849. doi: 10.1016/j.ebiom.2023.104849. Epub 2023 Oct 26. EBioMedicine. 2023. PMID: 37898095 Free PMC article.
Tyrosinase protects human melanocytes from ROS-generating compounds.
Perluigi M, De Marco F, Foppoli C, Coccia R, Blarzino C, Marcante ML, Cini C. Perluigi M, et al. Biochem Biophys Res Commun. 2003 May 30;305(2):250-6. doi: 10.1016/s0006-291x(03)00751-4. Biochem Biophys Res Commun. 2003. PMID: 12745066
The effects on the viability were studied by treating the cells with variable concentration of THP or SAL; both TIQs were well tolerated up to roughly 30 micro M. At higher concentrations, THP became overtly toxic while SAL showed no cytotoxic effect up to 100 micro M …
The effects on the viability were studied by treating the cells with variable concentration of THP or SAL; both TIQs were well tolerated up …
Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence.
Arena A, Zimmer TS, van Scheppingen J, Korotkov A, Anink JJ, Mühlebner A, Jansen FE, van Hecke W, Spliet WG, van Rijen PC, Vezzani A, Baayen JC, Idema S, Iyer AM, Perluigi M, Mills JD, van Vliet EA, Aronica E. Arena A, et al. Among authors: perluigi m. Brain Pathol. 2019 May;29(3):351-365. doi: 10.1111/bpa.12661. Epub 2018 Nov 20. Brain Pathol. 2019. PMID: 30303592 Free PMC article.
Expression of OS markers was positively correlated to expression of brain inflammation markers. In vitro, 100 M, but not 50 M, of H(2) O(2) increased expression of TLR4, IL-1beta and COX-2. We found that NF-kappaB signaling was activated only upon stimulation with 1 …
Expression of OS markers was positively correlated to expression of brain inflammation markers. In vitro, 100 M, but not 50 M, …
Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [(13)C2D4]RAD001 internal standard.
Giovagnoli S, Cassano T, Pace L, Magini A, Polchi A, Tancini B, Perluigi M, De Marco F, Emiliani C, Dolcetta D. Giovagnoli S, et al. Among authors: perluigi m. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 15;985:155-63. doi: 10.1016/j.jchromb.2015.01.035. Epub 2015 Feb 3. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 25682337
The QTOF MS detector was set to select RAD001 ammonium adducts (m/z 975.6152) and [(13)C2D4]RAD001 (m/z 981.6481). Two different UHPLC columns were preliminarily tested. ...
The QTOF MS detector was set to select RAD001 ammonium adducts (m/z 975.6152) and [(13)C2D4]RAD001 (m/z 981.6481). Two differe …