Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
1983 2
1984 2
1986 4
1987 5
1988 5
1989 8
1990 5
1991 11
1992 11
1993 22
1994 18
1995 13
1996 29
1997 23
1998 46
1999 35
2000 50
2001 52
2002 59
2003 66
2004 90
2005 110
2006 129
2007 118
2008 169
2009 185
2010 256
2011 290
2012 311
2013 387
2014 501
2015 609
2016 631
2017 714
2018 925
2019 973
2020 1141
2021 1396
2022 1567
2023 1605
2024 712

Text availability

Article attribute

Article type

Publication date

Search Results

11,901 results

Results by year

Filters applied: . Clear all
Page 1
N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.
Wang X, Zhao BS, Roundtree IA, Lu Z, Han D, Ma H, Weng X, Chen K, Shi H, He C. Wang X, et al. Among authors: shi h. Cell. 2015 Jun 4;161(6):1388-99. doi: 10.1016/j.cell.2015.05.014. Cell. 2015. PMID: 26046440 Free PMC article.
N(6)-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNA. This modification is reversible and non-stoichiometric and adds another layer to the dynamic control of mRNA metabolism. The stability of m(6)A-modified mRNA is regulated by a …
N(6)-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNA. This modification is reversible and non-st …
Dynamic control of chromatin-associated m(6)A methylation regulates nascent RNA synthesis.
Xu W, He C, Kaye EG, Li J, Mu M, Nelson GM, Dong L, Wang J, Wu F, Shi YG, Adelman K, Lan F, Shi Y, Shen H. Xu W, et al. Among authors: shi y, shi yg. Mol Cell. 2022 Mar 17;82(6):1156-1168.e7. doi: 10.1016/j.molcel.2022.02.006. Epub 2022 Feb 25. Mol Cell. 2022. PMID: 35219383 Free PMC article.
N(6)-methyladenosine (m(6)A) methylation is co-transcriptionally deposited on mRNA, but a possible role of m(6)A on transcription remains poorly understood. ...Consistently, we found the Integrator complex component INTS11 elevated at promoters and enhancers upon lo …
N(6)-methyladenosine (m(6)A) methylation is co-transcriptionally deposited on mRNA, but a possible role of m(6)A on transcript …
METTL3-m(6)A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Peng Z, Gong Y, Wang X, He W, Wu L, Zhang L, Xiong L, Huang Y, Su L, Shi P, Cao X, Liu R, Li Y, Xiao H. Peng Z, et al. Among authors: shi p. Mol Ther. 2022 Feb 2;30(2):932-946. doi: 10.1016/j.ymthe.2021.09.016. Epub 2021 Sep 20. Mol Ther. 2022. PMID: 34547464 Free PMC article.
However, the role of m(6)A modification in autophagy in nonalcoholic fatty liver disease (NAFLD) remains largely unknown. ...Mechanistically, METTL3 directly bound to Rubicon mRNA and mediated the m(6)A modification, while YTH N6-methyladenosine RNA binding protein …
However, the role of m(6)A modification in autophagy in nonalcoholic fatty liver disease (NAFLD) remains largely unknown. ...Mechanis …
Differential m(6)A, m(6)A(m), and m(1)A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.
Wei J, Liu F, Lu Z, Fei Q, Ai Y, He PC, Shi H, Cui X, Su R, Klungland A, Jia G, Chen J, He C. Wei J, et al. Among authors: shi h. Mol Cell. 2018 Sep 20;71(6):973-985.e5. doi: 10.1016/j.molcel.2018.08.011. Epub 2018 Sep 6. Mol Cell. 2018. PMID: 30197295 Free PMC article.
We find that FTO binds multiple RNA species, including mRNA, snRNA, and tRNA, and can demethylate internal m(6)A and cap m(6)A(m) in mRNA, internal m(6)A in U6 RNA, internal and cap m(6)A(m) in snRNAs, and N(1)-methyladenosine (m(1 …
We find that FTO binds multiple RNA species, including mRNA, snRNA, and tRNA, and can demethylate internal m(6)A and cap m(6)A …
Macrophage Polarization Modulated by NF-κB in Polylactide Membranes-Treated Peritendinous Adhesion.
Wang S, Lu M, Wang W, Yu S, Yu R, Cai C, Li Y, Shi Z, Zou J, He M, Xie W, Yu D, Jin H, Li H, Xiao W, Fan C, Wu F, Li Y, Liu S. Wang S, et al. Among authors: shi z. Small. 2022 Apr;18(13):e2104112. doi: 10.1002/smll.202104112. Epub 2021 Nov 23. Small. 2022. PMID: 34816589
It is hypothesized that NF-kappaB phosphorylation exerts a proinflammatory regulator in FBR to polylactide membranes (PLA-M) and adhesion. First, in vitro and in vivo experiments show that PLA-M induces NF-kappaB phosphorylation in macrophages, leading to M1 polariz …
It is hypothesized that NF-kappaB phosphorylation exerts a proinflammatory regulator in FBR to polylactide membranes (PLA-M) and adhe …
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
Shi H, Wang X, Lu Z, Zhao BS, Ma H, Hsu PJ, Liu C, He C. Shi H, et al. Cell Res. 2017 Mar;27(3):315-328. doi: 10.1038/cr.2017.15. Epub 2017 Jan 20. Cell Res. 2017. PMID: 28106072 Free PMC article.
It regulates multiple steps throughout the RNA life cycle including RNA processing, translation, and decay, via the recognition by selective binding proteins. In the cytoplasm, m(6)A binding protein YTHDF1 facilitates translation of m(6)A-modified mRNAs, and YTHDF2 …
It regulates multiple steps throughout the RNA life cycle including RNA processing, translation, and decay, via the recognition by selective …
RNA m(6)A Modification in Cancers: Molecular Mechanisms and Potential Clinical Applications.
Gu C, Shi X, Dai C, Shen F, Rocco G, Chen J, Huang Z, Chen C, He C, Huang T, Chen C. Gu C, et al. Among authors: shi x. Innovation (Camb). 2020 Nov 4;1(3):100066. doi: 10.1016/j.xinn.2020.100066. eCollection 2020 Nov 25. Innovation (Camb). 2020. PMID: 34557726 Free PMC article. Review.
Thereby the dysregulation of m(6)A may lead to tumorigenesis and progression. Given the tumorigenic role of abnormal m(6)A expression, m(6)A regulators may function as potential clinical therapeutic targets for cancers. In this review, we emphasize on the und …
Thereby the dysregulation of m(6)A may lead to tumorigenesis and progression. Given the tumorigenic role of abnormal m(6)A exp …
METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m(6)A modification.
Xu Y, Lv D, Yan C, Su H, Zhang X, Shi Y, Ying K. Xu Y, et al. Among authors: shi y. Cancer Cell Int. 2022 Jan 7;22(1):11. doi: 10.1186/s12935-021-02433-6. Cancer Cell Int. 2022. PMID: 34996469 Free PMC article.
BACKGROUND: N6-methyladenosine (m(6)A) has emerged as a significant regulator of the progress of various cancers. ...Additionally, we demonstrated that YTHDF1, a m(6)A reader, was recruited by METTL3 to enhance SLC7A11 m(6)A modification. ...
BACKGROUND: N6-methyladenosine (m(6)A) has emerged as a significant regulator of the progress of various cancers. ...Additionally, we …
The RNA N6-methyladenosine modification landscape of human fetal tissues.
Xiao S, Cao S, Huang Q, Xia L, Deng M, Yang M, Jia G, Liu X, Shi J, Wang W, Li Y, Liu S, Zhu H, Tan K, Luo Q, Zhong M, He C, Xia L. Xiao S, et al. Among authors: shi j. Nat Cell Biol. 2019 May;21(5):651-661. doi: 10.1038/s41556-019-0315-4. Epub 2019 Apr 29. Nat Cell Biol. 2019. PMID: 31036937
Here, to explore the global landscape of m(6)A in human tissues, we generated 21 whole-transcriptome m(6)A methylomes across major fetal tissues using m(6)A sequencing. These data reveal dynamic m(6)A methylation, identify large numbers of tissue diffe …
Here, to explore the global landscape of m(6)A in human tissues, we generated 21 whole-transcriptome m(6)A methylomes across m …
m(6)A-binding proteins: the emerging crucial performers in epigenetics.
Zhao Y, Shi Y, Shen H, Xie W. Zhao Y, et al. Among authors: shi y. J Hematol Oncol. 2020 Apr 10;13(1):35. doi: 10.1186/s13045-020-00872-8. J Hematol Oncol. 2020. PMID: 32276589 Free PMC article. Review.
N(6)-methyladenosine (m(6)A) is a well-known post-transcriptional modification that is the most common type of methylation in eukaryotic mRNAs. The regulation of m(6)A is dynamic and reversible, which is erected by m(6)A methyltransferases ("writers") and rem …
N(6)-methyladenosine (m(6)A) is a well-known post-transcriptional modification that is the most common type of methylation in eukaryo …
11,901 results
You have reached the last available page of results. Please see the User Guide for more information.