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Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites.
Dixelius J, Makinen T, Wirzenius M, Karkkainen MJ, Wernstedt C, Alitalo K, Claesson-Welsh L. Dixelius J, et al. Among authors: makinen t. J Biol Chem. 2003 Oct 17;278(42):40973-9. doi: 10.1074/jbc.M304499200. Epub 2003 Jul 24. J Biol Chem. 2003. PMID: 12881528 Free article.
The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.
Aspelund A, Tammela T, Antila S, Nurmi H, Leppänen VM, Zarkada G, Stanczuk L, Francois M, Mäkinen T, Saharinen P, Immonen I, Alitalo K. Aspelund A, et al. Among authors: makinen t. J Clin Invest. 2014 Sep;124(9):3975-86. doi: 10.1172/JCI75395. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061878 Free PMC article.
VEGFR3 does not sustain retinal angiogenesis without VEGFR2.
Zarkada G, Heinolainen K, Makinen T, Kubota Y, Alitalo K. Zarkada G, et al. Among authors: makinen t. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):761-6. doi: 10.1073/pnas.1423278112. Epub 2015 Jan 5. Proc Natl Acad Sci U S A. 2015. PMID: 25561555 Free PMC article.
Nonvenous origin of dermal lymphatic vasculature.
Martinez-Corral I, Ulvmar MH, Stanczuk L, Tatin F, Kizhatil K, John SW, Alitalo K, Ortega S, Makinen T. Martinez-Corral I, et al. Among authors: makinen t. Circ Res. 2015 May 8;116(10):1649-54. doi: 10.1161/CIRCRESAHA.116.306170. Epub 2015 Mar 3. Circ Res. 2015. PMID: 25737499
cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels.
Stanczuk L, Martinez-Corral I, Ulvmar MH, Zhang Y, Laviña B, Fruttiger M, Adams RH, Saur D, Betsholtz C, Ortega S, Alitalo K, Graupera M, Mäkinen T. Stanczuk L, et al. Among authors: makinen t. Cell Rep. 2015 Mar 17;10(10):1708-1721. doi: 10.1016/j.celrep.2015.02.026. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772358 Free article.
286 results