Médard G - Search Results

1

Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.

Arduino DM, Wettmarshausen J, Vais H, Navas-Navarro P, Cheng Y, Leimpek A, Ma Z, Delrio-Lorenzo A, Giordano A, Garcia-Perez C, Médard G, Kuster B, García-Sancho J, Mokranjac D, Foskett JK, Alonso MT, Perocchi F. Arduino DM, et al. Among authors: medard g. Mol Cell. 2017 Aug 17;67(4):711-723.e7. doi: 10.1016/j.molcel.2017.07.019. Mol Cell. 2017. PMID: 28820965 Free PMC article.

2

Characterization of a chemical affinity probe targeting Akt kinases.

Pachl F, Plattner P, Ruprecht B, Médard G, Sewald N, Kuster B. Pachl F, et al. Among authors: medard g. J Proteome Res. 2013 Aug 2;12(8):3792-800. doi: 10.1021/pr400455j. Epub 2013 Jul 3. J Proteome Res. 2013. PMID: 23795919

3

DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.

Hahne H, Pachl F, Ruprecht B, Maier SK, Klaeger S, Helm D, Médard G, Wilm M, Lemeer S, Kuster B. Hahne H, et al. Among authors: medard g. Nat Methods. 2013 Oct;10(10):989-91. doi: 10.1038/nmeth.2610. Epub 2013 Aug 25. Nat Methods. 2013. PMID: 23975139

4

A new chemical probe for quantitative proteomic profiling of fibroblast growth factor receptor and its inhibitors.

Ku X, Heinzlmeir S, Liu X, Médard G, Kuster B. Ku X, et al. Among authors: medard g. J Proteomics. 2014 Jan 16;96:44-55. doi: 10.1016/j.jprot.2013.10.031. Epub 2013 Oct 31. J Proteomics. 2014. PMID: 24184958

5

New affinity probe targeting VEGF receptors for kinase inhibitor selectivity profiling by chemical proteomics.

Ku X, Heinzlmeir S, Helm D, Médard G, Kuster B. Ku X, et al. Among authors: medard g. J Proteome Res. 2014 May 2;13(5):2445-52. doi: 10.1021/pr401247t. Epub 2014 Apr 22. J Proteome Res. 2014. PMID: 24712744

6

Comprehensive and reproducible phosphopeptide enrichment using iron immobilized metal ion affinity chromatography (Fe-IMAC) columns.

Ruprecht B, Koch H, Medard G, Mundt M, Kuster B, Lemeer S. Ruprecht B, et al. Among authors: medard g. Mol Cell Proteomics. 2015 Jan;14(1):205-15. doi: 10.1074/mcp.M114.043109. Epub 2014 Nov 13. Mol Cell Proteomics. 2015. PMID: 25394399 Free PMC article.

7

Optimized chemical proteomics assay for kinase inhibitor profiling.

Médard G, Pachl F, Ruprecht B, Klaeger S, Heinzlmeir S, Helm D, Qiao H, Ku X, Wilhelm M, Kuehne T, Wu Z, Dittmann A, Hopf C, Kramer K, Kuster B. Médard G, et al. J Proteome Res. 2015 Mar 6;14(3):1574-86. doi: 10.1021/pr5012608. Epub 2015 Feb 20. J Proteome Res. 2015. PMID: 25660469

8

Chemical Proteomics Uncovers EPHA2 as a Mechanism of Acquired Resistance to Small Molecule EGFR Kinase Inhibition.

Koch H, Busto ME, Kramer K, Médard G, Kuster B. Koch H, et al. Among authors: medard g. J Proteome Res. 2015 Jun 5;14(6):2617-25. doi: 10.1021/acs.jproteome.5b00161. Epub 2015 May 26. J Proteome Res. 2015. PMID: 25963923

9

Evaluation of Kinase Activity Profiling Using Chemical Proteomics.

Ruprecht B, Zecha J, Heinzlmeir S, Médard G, Lemeer S, Kuster B. Ruprecht B, et al. Among authors: medard g. ACS Chem Biol. 2015 Dec 18;10(12):2743-52. doi: 10.1021/acschembio.5b00616. Epub 2015 Oct 5. ACS Chem Biol. 2015. PMID: 26378887

10

Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.

Klaeger S, Gohlke B, Perrin J, Gupta V, Heinzlmeir S, Helm D, Qiao H, Bergamini G, Handa H, Savitski MM, Bantscheff M, Médard G, Preissner R, Kuster B. Klaeger S, et al. Among authors: medard g. ACS Chem Biol. 2016 May 20;11(5):1245-54. doi: 10.1021/acschembio.5b01063. Epub 2016 Feb 25. ACS Chem Biol. 2016. PMID: 26863403

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