Möröy T - Search Results

1

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.

Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, Vargel O, Wilson NK, Möröy T, Bonifer C, Göttgens B, Kouskoff V, Lacaud G. Lancrin C, et al. Among authors: moroy t. Blood. 2012 Jul 12;120(2):314-22. doi: 10.1182/blood-2011-10-386094. Epub 2012 Jun 5. Blood. 2012. PMID: 22668850 Free article.

2

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1.

Thambyrajah R, Mazan M, Patel R, Moignard V, Stefanska M, Marinopoulou E, Li Y, Lancrin C, Clapes T, Möröy T, Robin C, Miller C, Cowley S, Göttgens B, Kouskoff V, Lacaud G. Thambyrajah R, et al. Among authors: moroy t. Nat Cell Biol. 2016 Jan;18(1):21-32. doi: 10.1038/ncb3276. Epub 2015 Nov 30. Nat Cell Biol. 2016. PMID: 26619147

3

From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation.

Möröy T, Vassen L, Wilkes B, Khandanpour C. Möröy T, et al. Blood. 2015 Dec 10;126(24):2561-9. doi: 10.1182/blood-2015-06-655043. Epub 2015 Oct 7. Blood. 2015. PMID: 26447191 Free PMC article. Review.

4

Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1.

Vassen L, Okayama T, Möröy T. Vassen L, et al. Among authors: moroy t. Blood. 2007 Mar 15;109(6):2356-64. doi: 10.1182/blood-2006-06-030031. Epub 2006 Nov 9. Blood. 2007. PMID: 17095621 Free article.

5

A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia.

Khandanpour C, Thiede C, Valk PJ, Sharif-Askari E, Nückel H, Lohmann D, Horsthemke B, Siffert W, Neubauer A, Grzeschik KH, Bloomfield CD, Marcucci G, Maharry K, Slovak ML, van der Reijden BA, Jansen JH, Schackert HK, Afshar K, Schnittger S, Peeters JK, Kroschinsky F, Ehninger G, Lowenberg B, Dührsen U, Möröy T. Khandanpour C, et al. Among authors: moroy t. Blood. 2010 Mar 25;115(12):2462-72. doi: 10.1182/blood-2009-08-239822. Epub 2010 Jan 14. Blood. 2010. PMID: 20075157 Free PMC article.

6

Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells.

Khandanpour C, Sharif-Askari E, Vassen L, Gaudreau MC, Zhu J, Paul WE, Okayama T, Kosan C, Möröy T. Khandanpour C, et al. Among authors: moroy t. Blood. 2010 Dec 9;116(24):5149-61. doi: 10.1182/blood-2010-04-280305. Epub 2010 Sep 8. Blood. 2010. PMID: 20826720 Free PMC article.

7

Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1.

Schulz D, Vassen L, Chow KT, McWhirter SM, Amin RH, Möröy T, Schlissel MS. Schulz D, et al. Among authors: moroy t. J Exp Med. 2012 Jan 16;209(1):187-99. doi: 10.1084/jem.20110645. Epub 2011 Dec 26. J Exp Med. 2012. PMID: 22201127 Free PMC article.

8

The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice.

Khandanpour C, Krongold J, Schütte J, Bouwman F, Vassen L, Gaudreau MC, Chen R, Calero-Nieto FJ, Diamanti E, Hannah R, Meyer SE, Grimes HL, van der Reijden BA, Jansen JH, Patel CV, Peeters JK, Löwenberg B, Dührsen U, Göttgens B, Möröy T. Khandanpour C, et al. Among authors: moroy t. Blood. 2012 Nov 8;120(19):4006-17. doi: 10.1182/blood-2011-02-334722. Epub 2012 Aug 28. Blood. 2012. PMID: 22932805 Free article.

9

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

Shooshtarizadeh P, Helness A, Vadnais C, Brouwer N, Beauchemin H, Chen R, Bagci H, Staal FJT, Coté JF, Möröy T. Shooshtarizadeh P, et al. Among authors: moroy t. Nat Commun. 2019 Mar 20;10(1):1270. doi: 10.1038/s41467-019-09273-z. Nat Commun. 2019. PMID: 30894540 Free PMC article.

10

CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.

Ligons DL, Tuncer C, Linowes BA, Akcay IM, Kurtulus S, Deniz E, Atasever Arslan B, Cevik SI, Keller HR, Luckey MA, Feigenbaum L, Möröy T, Ersahin T, Atalay R, Erman B, Park JH. Ligons DL, et al. Among authors: moroy t. J Biol Chem. 2012 Oct 5;287(41):34386-99. doi: 10.1074/jbc.M112.378687. Epub 2012 Aug 3. J Biol Chem. 2012. PMID: 22865857 Free PMC article.

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