Müller A - Search Results

1

Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors.

Heppner KM, Piechowski CL, Müller A, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, Dimarchi R, Biebermann H, Tschöp MH, Sandoval DA, Perez-Tilve D. Heppner KM, et al. Among authors: muller a. Diabetes. 2014 Jan;63(1):122-31. doi: 10.2337/db13-0414. Epub 2013 Sep 23. Diabetes. 2014. PMID: 24062249 Free PMC article.

2

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.

Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. Müller TD, et al. Among authors: muller a. Nat Commun. 2013;4:1968. doi: 10.1038/ncomms2968. Nat Commun. 2013. PMID: 23744028 Free PMC article.

3

G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.

Müller A, Kleinau G, Piechowski CL, Müller TD, Finan B, Pratzka J, Grüters A, Krude H, Tschöp M, Biebermann H. Müller A, et al. Among authors: muller td. PLoS One. 2013;8(1):e53347. doi: 10.1371/journal.pone.0053347. Epub 2013 Jan 15. PLoS One. 2013. PMID: 23335960 Free PMC article.

4

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.

Gomes I, Bobeck EN, Margolis EB, Gupta A, Sierra S, Fakira AK, Fujita W, Müller TD, Müller A, Tschöp MH, Kleinau G, Fricker LD, Devi LA. Gomes I, et al. Among authors: muller a, muller td. Sci Signal. 2016 Apr 26;9(425):ra43. doi: 10.1126/scisignal.aad0694. Sci Signal. 2016. PMID: 27117253 Free PMC article.

5

The extracellular N-terminal domain of G-protein coupled receptor 83 regulates signaling properties and is an intramolecular inverse agonist.

Müller A, Leinweber B, Fischer J, Müller TD, Grüters A, Tschöp MH, Knäuper V, Biebermann H, Kleinau G. Müller A, et al. Among authors: muller td. BMC Res Notes. 2014 Dec 16;7:913. doi: 10.1186/1756-0500-7-913. BMC Res Notes. 2014. PMID: 25516095 Free PMC article.

6

Oligomerization of GPCRs involved in endocrine regulation.

Kleinau G, Müller A, Biebermann H. Kleinau G, et al. Among authors: muller a. J Mol Endocrinol. 2016 Jul;57(1):R59-80. doi: 10.1530/JME-16-0049. Epub 2016 May 5. J Mol Endocrinol. 2016. PMID: 27151573 Review.

7

Inhibition of melanocortin-4 receptor dimerization by substitutions in intracellular loop 2.

Piechowski CL, Rediger A, Lagemann C, Mühlhaus J, Müller A, Pratzka J, Tarnow P, Grüters A, Krude H, Kleinau G, Biebermann H. Piechowski CL, et al. Among authors: muller a. J Mol Endocrinol. 2013 Jun 29;51(1):109-18. doi: 10.1530/JME-13-0061. Print 2013. J Mol Endocrinol. 2013. PMID: 23674133

8

Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83.

Müller A, Berkmann JC, Scheerer P, Biebermann H, Kleinau G. Müller A, et al. PLoS One. 2016 Dec 9;11(12):e0168260. doi: 10.1371/journal.pone.0168260. eCollection 2016. PLoS One. 2016. PMID: 27936173 Free PMC article.

9

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency.

Clément K, Biebermann H, Farooqi IS, Van der Ploeg L, Wolters B, Poitou C, Puder L, Fiedorek F, Gottesdiener K, Kleinau G, Heyder N, Scheerer P, Blume-Peytavi U, Jahnke I, Sharma S, Mokrosinski J, Wiegand S, Müller A, Weiß K, Mai K, Spranger J, Grüters A, Blankenstein O, Krude H, Kühnen P. Clément K, et al. Among authors: muller a. Nat Med. 2018 May;24(5):551-555. doi: 10.1038/s41591-018-0015-9. Epub 2018 May 7. Nat Med. 2018. PMID: 29736023 Clinical Trial.

10

3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling.

Dinter J, Mühlhaus J, Jacobi SF, Wienchol CL, Cöster M, Meister J, Hoefig CS, Müller A, Köhrle J, Grüters A, Krude H, Mittag J, Schöneberg T, Kleinau G, Biebermann H. Dinter J, et al. Among authors: muller a. J Mol Endocrinol. 2015 Jun;54(3):205-16. doi: 10.1530/JME-15-0003. Epub 2015 Apr 15. J Mol Endocrinol. 2015. PMID: 25878061

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