MC_UU_00016/4/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	9
2018	6
2019	4
2020	10
2021	10
2022	4
2024	0

1

On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation.

Jeziorska DM, Tunnacliffe EAJ, Brown JM, Ayyub H, Sloane-Stanley J, Sharpe JA, Lagerholm BC, Babbs C, Smith AJH, Buckle VJ, Higgs DR. Jeziorska DM, et al. Nat Commun. 2022 Nov 4;13(1):6641. doi: 10.1038/s41467-022-33977-4. Nat Commun. 2022. PMID: 36333299 Free PMC article.

2

LanceOtron: a deep learning peak caller for genome sequencing experiments.

Hentges LD, Sergeant MJ, Cole CB, Downes DJ, Hughes JR, Taylor S. Hentges LD, et al. Bioinformatics. 2022 Sep 15;38(18):4255-4263. doi: 10.1093/bioinformatics/btac525. Bioinformatics. 2022. PMID: 35866989 Free PMC article.

3

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin.

Truch J, Downes DJ, Scott C, Gür ER, Telenius JM, Repapi E, Schwessinger R, Gosden M, Brown JM, Taylor S, Cheong PL, Hughes JR, Higgs DR, Gibbons RJ. Truch J, et al. Nat Commun. 2022 Jun 17;13(1):3485. doi: 10.1038/s41467-022-31194-7. Nat Commun. 2022. PMID: 35710802 Free PMC article.

4

Scalable in vitro production of defined mouse erythroblasts.

Francis HS, Harold CL, Beagrie RA, King AJ, Gosden ME, Blayney JW, Jeziorska DM, Babbs C, Higgs DR, Kassouf MT. Francis HS, et al. PLoS One. 2022 Jan 7;17(1):e0261950. doi: 10.1371/journal.pone.0261950. eCollection 2022. PLoS One. 2022. PMID: 34995303 Free PMC article.

5

Publisher Correction: The relationship between genome structure and function.

Oudelaar AM, Higgs DR. Oudelaar AM, et al. Nat Rev Genet. 2021 Dec;22(12):808. doi: 10.1038/s41576-021-00425-w. Nat Rev Genet. 2021. PMID: 34650258 No abstract available.

6

Testing the super-enhancer concept.

Blobel GA, Higgs DR, Mitchell JA, Notani D, Young RA. Blobel GA, et al. Nat Rev Genet. 2021 Dec;22(12):749-755. doi: 10.1038/s41576-021-00398-w. Epub 2021 Sep 3. Nat Rev Genet. 2021. PMID: 34480110 No abstract available.

7

Reactivation of a developmentally silenced embryonic globin gene.

King AJ, Songdej D, Downes DJ, Beagrie RA, Liu S, Buckley M, Hua P, Suciu MC, Marieke Oudelaar A, Hanssen LLP, Jeziorska D, Roberts N, Carpenter SJ, Francis H, Telenius J, Olijnik AA, Sharpe JA, Sloane-Stanley J, Eglinton J, Kassouf MT, Orkin SH, Pennacchio LA, Davies JOJ, Hughes JR, Higgs DR, Babbs C. King AJ, et al. Nat Commun. 2021 Jul 21;12(1):4439. doi: 10.1038/s41467-021-24402-3. Nat Commun. 2021. PMID: 34290235 Free PMC article.

8

A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker.

Bozhilov YK, Downes DJ, Telenius J, Marieke Oudelaar A, Olivier EN, Mountford JC, Hughes JR, Gibbons RJ, Higgs DR. Bozhilov YK, et al. Nat Commun. 2021 Jun 21;12(1):3806. doi: 10.1038/s41467-021-23980-6. Nat Commun. 2021. PMID: 34155213 Free PMC article.

9

Defining genome architecture at base-pair resolution.

Hua P, Badat M, Hanssen LLP, Hentges LD, Crump N, Downes DJ, Jeziorska DM, Oudelaar AM, Schwessinger R, Taylor S, Milne TA, Hughes JR, Higgs DR, Davies JOJ. Hua P, et al. Nature. 2021 Jul;595(7865):125-129. doi: 10.1038/s41586-021-03639-4. Epub 2021 Jun 9. Nature. 2021. PMID: 34108683

10

Author Correction: Enhancer-promoter interactions and transcription.

Higgs DR. Higgs DR. Nat Genet. 2021 May;53(5):761. doi: 10.1038/s41588-021-00815-0. Nat Genet. 2021. PMID: 33658687 No abstract available.

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