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Page 1
Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation.
Stanley CP, Maghzal GJ, Ayer A, Talib J, Giltrap AM, Shengule S, Wolhuter K, Wang Y, Chadha P, Suarna C, Prysyazhna O, Scotcher J, Dunn LL, Prado FM, Nguyen N, Odiba JO, Baell JB, Stasch JP, Yamamoto Y, Di Mascio P, Eaton P, Payne RJ, Stocker R. Stanley CP, et al. Nature. 2019 Feb;566(7745):548-552. doi: 10.1038/s41586-019-0947-3. Epub 2019 Feb 13. Nature. 2019. PMID: 30760924
PKG1α oxidation negatively regulates food seeking behaviour and reward.
Duraffourd C, Huckstepp RTR, Braren I, Fernandes C, Brock O, Delogu A, Prysyazhna O, Burgoyne J, Eaton P. Duraffourd C, et al. Redox Biol. 2019 Feb;21:101077. doi: 10.1016/j.redox.2018.101077. Epub 2018 Dec 18. Redox Biol. 2019. PMID: 30593979 Free PMC article.
The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.
De Nicola GF, Bassi R, Nichols C, Fernandez-Caggiano M, Golforoush PA, Thapa D, Anderson R, Martin ED, Verma S, Kleinjung J, Laing A, Hutchinson JP, Eaton P, Clark J, Marber MS. De Nicola GF, et al. JCI Insight. 2018 Aug 23;3(16):e121144. doi: 10.1172/jci.insight.121144. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135318 Free PMC article.
Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity.
Donzelli S, Goetz M, Schmidt K, Wolters M, Stathopoulou K, Diering S, Prysyazhna O, Polat V, Scotcher J, Dees C, Subramanian H, Butt E, Kamynina A, Schobesberger S, King SB, Nikolaev VO, de Wit C, Leichert LI, Feil R, Eaton P, Cuello F. Donzelli S, et al. Sci Rep. 2017 Aug 30;7(1):9938. doi: 10.1038/s41598-017-09275-1. Sci Rep. 2017. PMID: 28855531 Free PMC article.
32 results