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Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function.
Bian Z, Wang Q, Zhou X, Tan T, Park KH, Kramer HF, McDougal A, Laping NJ, Kumar S, Adesanya TMA, Sermersheim M, Yi F, Wang X, Wu J, Gumpper K, Jiang Q, He D, Lin PH, Li H, Guan F, Zhou J, Kohr MJ, Zeng C, Zhu H, Ma J. Bian Z, et al. Among authors: ma j. Nat Commun. 2019 Oct 11;10(1):4659. doi: 10.1038/s41467-019-12483-0. Nat Commun. 2019. PMID: 31604915 Free PMC article.
MG53-mediated cell membrane repair protects against acute kidney injury.
Duann P, Li H, Lin P, Tan T, Wang Z, Chen K, Zhou X, Gumpper K, Zhu H, Ludwig T, Mohler PJ, Rovin B, Abraham WT, Zeng C, Ma J. Duann P, et al. Among authors: ma j. Sci Transl Med. 2015 Mar 18;7(279):279ra36. doi: 10.1126/scitranslmed.3010755. Sci Transl Med. 2015. PMID: 25787762 Free PMC article.
MG53 permeates through blood-brain barrier to protect ischemic brain injury.
Yao Y, Zhang B, Zhu H, Li H, Han Y, Chen K, Wang Z, Zeng J, Liu Y, Wang X, Li Y, He D, Lin P, Zhou X, Park KH, Bian Z, Chen Z, Gong N, Tan T, Zhou J, Zhang M, Ma J, Zeng C. Yao Y, et al. Among authors: ma j. Oncotarget. 2016 Apr 19;7(16):22474-85. doi: 10.18632/oncotarget.7965. Oncotarget. 2016. PMID: 26967557 Free PMC article.
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