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The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia.
Maat H, Atsma TJ, Hogeling SM, Rodríguez López A, Jaques J, Olthuis M, de Vries MP, Gravesteijn C, Brouwers-Vos AZ, van der Meer N, Datema S, Salzbrunn J, Huls G, Baas R, Martens JHA, van den Boom V, Schuringa JJ. Maat H, et al. iScience. 2021 Apr 16;24(5):102435. doi: 10.1016/j.isci.2021.102435. eCollection 2021 May 21. iScience. 2021. PMID: 34113809 Free PMC article.
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis.
van den Boom V, Maat H, Geugien M, Rodríguez López A, Sotoca AM, Jaques J, Brouwers-Vos AZ, Fusetti F, Groen RW, Yuan H, Martens AC, Stunnenberg HG, Vellenga E, Martens JH, Schuringa JJ. van den Boom V, et al. Among authors: maat h. Cell Rep. 2016 Jan 12;14(2):332-46. doi: 10.1016/j.celrep.2015.12.034. Epub 2015 Dec 31. Cell Rep. 2016. PMID: 26748712 Free article.
Dual role of miR-21 in CD4+ T-cells: activation-induced miR-21 supports survival of memory T-cells and regulates CCR7 expression in naive T-cells.
Smigielska-Czepiel K, van den Berg A, Jellema P, Slezak-Prochazka I, Maat H, van den Bos H, van der Lei RJ, Kluiver J, Brouwer E, Boots AM, Kroesen BJ. Smigielska-Czepiel K, et al. Among authors: maat h. PLoS One. 2013 Oct 1;8(10):e76217. doi: 10.1371/journal.pone.0076217. eCollection 2013. PLoS One. 2013. PMID: 24098447 Free PMC article.
33 results