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ER-directed TREX1 limits cGAS activation at micronuclei.
Mohr L, Toufektchan E, von Morgen P, Chu K, Kapoor A, Maciejowski J. Mohr L, et al. Among authors: maciejowski j. Mol Cell. 2021 Feb 18;81(4):724-738.e9. doi: 10.1016/j.molcel.2020.12.037. Epub 2021 Jan 20. Mol Cell. 2021. PMID: 33476576 Free PMC article.
Chromothripsis and Kataegis Induced by Telomere Crisis.
Maciejowski J, Li Y, Bosco N, Campbell PJ, de Lange T. Maciejowski J, et al. Cell. 2015 Dec 17;163(7):1641-54. doi: 10.1016/j.cell.2015.11.054. Cell. 2015. PMID: 26687355 Free PMC article.
The ins and outs of telomere crisis in cancer.
von Morgen P, Maciejowski J. von Morgen P, et al. Among authors: maciejowski j. Genome Med. 2018 Nov 27;10(1):89. doi: 10.1186/s13073-018-0596-4. Genome Med. 2018. PMID: 30482235 Free PMC article.
Purification of micronuclei from cultured cells by flow cytometry.
Toufektchan E, Maciejowski J. Toufektchan E, et al. Among authors: maciejowski j. STAR Protoc. 2021 Mar 18;2(1):100378. doi: 10.1016/j.xpro.2021.100378. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33778777 Free PMC article.
Mechanisms of APOBEC3 mutagenesis in human cancer cells.
Petljak M, Dananberg A, Chu K, Bergstrom EN, Striepen J, von Morgen P, Chen Y, Shah H, Sale JE, Alexandrov LB, Stratton MR, Maciejowski J. Petljak M, et al. Among authors: maciejowski j. Nature. 2022 Jul;607(7920):799-807. doi: 10.1038/s41586-022-04972-y. Epub 2022 Jul 20. Nature. 2022. PMID: 35859169 Free PMC article.
Epigenetic dysregulation from chromosomal transit in micronuclei.
Agustinus AS, Al-Rawi D, Dameracharla B, Raviram R, Jones BSCL, Stransky S, Scipioni L, Luebeck J, Di Bona M, Norkunaite D, Myers RM, Duran M, Choi S, Weigelt B, Yomtoubian S, McPherson A, Toufektchan E, Keuper K, Mischel PS, Mittal V, Shah SP, Maciejowski J, Storchova Z, Gratton E, Ly P, Landau D, Bakhoum MF, Koche RP, Sidoli S, Bafna V, David Y, Bakhoum SF. Agustinus AS, et al. Among authors: maciejowski j. Nature. 2023 Jul;619(7968):176-183. doi: 10.1038/s41586-023-06084-7. Epub 2023 Jun 7. Nature. 2023. PMID: 37286593 Free PMC article.
Intratumoral TREX1 induction promotes immune evasion by limiting type I interferon.
Toufektchan E, Dananberg A, Striepen J, Hickling JH, Shim A, Chen Y, Nichols A, Duran Paez MA, Mohr L, Bakhoum SF, Maciejowski J. Toufektchan E, et al. Among authors: maciejowski j. Cancer Immunol Res. 2024 Feb 26. doi: 10.1158/2326-6066.CIR-23-1093. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38408184
36 results