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A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris.
Cerini F, Gaertner H, Madden K, Tolstorukov I, Brown S, Laukens B, Callewaert N, Harner JC, Oommen AM, Harms JT, Sump AR, Sealock RC, Peterson DJ, Johnson SK, Abramson SB, Meagher M, Offord R, Hartley O. Cerini F, et al. Among authors: madden k. Protein Expr Purif. 2016 Mar;119:1-10. doi: 10.1016/j.pep.2015.10.011. Epub 2015 Oct 24. Protein Expr Purif. 2016. PMID: 26506568 Free PMC article.
Expression in the yeast Pichia pastoris.
Cregg JM, Tolstorukov I, Kusari A, Sunga J, Madden K, Chappell T. Cregg JM, et al. Among authors: madden k. Methods Enzymol. 2009;463:169-89. doi: 10.1016/S0076-6879(09)63013-5. Methods Enzymol. 2009. PMID: 19892173 Review.
Refined Pichia pastoris reference genome sequence.
Sturmberger L, Chappell T, Geier M, Krainer F, Day KJ, Vide U, Trstenjak S, Schiefer A, Richardson T, Soriaga L, Darnhofer B, Birner-Gruenberger R, Glick BS, Tolstorukov I, Cregg J, Madden K, Glieder A. Sturmberger L, et al. Among authors: madden k. J Biotechnol. 2016 Oct 10;235:121-31. doi: 10.1016/j.jbiotec.2016.04.023. Epub 2016 Apr 12. J Biotechnol. 2016. PMID: 27084056 Free PMC article. Review.
Bioprocess performance analysis of novel methanol-independent promoters for recombinant protein production with Pichia pastoris.
Garrigós-Martínez J, Vuoristo K, Nieto-Taype MA, Tähtiharju J, Uusitalo J, Tukiainen P, Schmid C, Tolstorukov I, Madden K, Penttilä M, Montesinos-Seguí JL, Valero F, Glieder A, Garcia-Ortega X. Garrigós-Martínez J, et al. Among authors: madden k. Microb Cell Fact. 2021 Mar 23;20(1):74. doi: 10.1186/s12934-021-01564-9. Microb Cell Fact. 2021. PMID: 33757505 Free PMC article.
Pichia pastoris as a host system for transformations.
Cregg JM, Barringer KJ, Hessler AY, Madden KR. Cregg JM, et al. Among authors: madden kr. Mol Cell Biol. 1985 Dec;5(12):3376-85. doi: 10.1128/mcb.5.12.3376-3385.1985. Mol Cell Biol. 1985. PMID: 3915774 Free PMC article.
567 results