Maechler P - Search Results

1

Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions.

Hinca SB, Salcedo C, Wagner A, Goldeman C, Sadat E, Aibar MMD, Maechler P, Brodin B, Aldana BI, Helms HCC. Hinca SB, et al. Among authors: maechler p. J Neurochem. 2021 Jun;157(6):1861-1875. doi: 10.1111/jnc.15207. Epub 2020 Oct 25. J Neurochem. 2021. PMID: 33025588 Free article.

2

Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.

Carobbio S, Ishihara H, Fernandez-Pascual S, Bartley C, Martin-Del-Rio R, Maechler P. Carobbio S, et al. Among authors: maechler p. Diabetologia. 2004 Feb;47(2):266-76. doi: 10.1007/s00125-003-1306-2. Epub 2003 Dec 20. Diabetologia. 2004. PMID: 14689183

3

Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis.

Frigerio F, Casimir M, Carobbio S, Maechler P. Frigerio F, et al. Among authors: maechler p. Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):965-72. doi: 10.1016/j.bbabio.2008.04.031. Epub 2008 Apr 30. Biochim Biophys Acta. 2008. PMID: 18486589 Free article. Review.

4

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P. Carobbio S, et al. Among authors: maechler p. J Biol Chem. 2009 Jan 9;284(2):921-9. doi: 10.1074/jbc.M806295200. Epub 2008 Nov 17. J Biol Chem. 2009. PMID: 19015267 Free article.

5

From pancreatic islets to central nervous system, the importance of glutamate dehydrogenase for the control of energy homeostasis.

Karaca M, Frigerio F, Maechler P. Karaca M, et al. Among authors: maechler p. Neurochem Int. 2011 Sep;59(4):510-7. doi: 10.1016/j.neuint.2011.03.024. Epub 2011 May 12. Neurochem Int. 2011. PMID: 21600947 Review.

6

Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.

Vetterli L, Carobbio S, Pournourmohammadi S, Martin-Del-Rio R, Skytt DM, Waagepetersen HS, Tamarit-Rodriguez J, Maechler P. Vetterli L, et al. Among authors: maechler p. Mol Biol Cell. 2012 Oct;23(19):3851-62. doi: 10.1091/mbc.E11-08-0676. Epub 2012 Aug 8. Mol Biol Cell. 2012. PMID: 22875990 Free PMC article.

7

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.

Frigerio F, Karaca M, De Roo M, Mlynárik V, Skytt DM, Carobbio S, Pajęcka K, Waagepetersen HS, Gruetter R, Muller D, Maechler P. Frigerio F, et al. Among authors: maechler p. J Neurochem. 2012 Nov;123(3):342-8. doi: 10.1111/j.1471-4159.2012.07933.x. Epub 2012 Sep 28. J Neurochem. 2012. PMID: 22924626 Free article.

8

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.

Karaca M, Frigerio F, Migrenne S, Martin-Levilain J, Skytt DM, Pajecka K, Martin-del-Rio R, Gruetter R, Tamarit-Rodriguez J, Waagepetersen HS, Magnan C, Maechler P. Karaca M, et al. Among authors: maechler p. Cell Rep. 2015 Oct 13;13(2):365-75. doi: 10.1016/j.celrep.2015.09.003. Epub 2015 Oct 1. Cell Rep. 2015. PMID: 26440896 Free article.

9

Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?

Pournourmohammadi S, Grimaldi M, Stridh MH, Lavallard V, Waagepetersen HS, Wollheim CB, Maechler P. Pournourmohammadi S, et al. Among authors: maechler p. Int J Biochem Cell Biol. 2017 Jul;88:220-225. doi: 10.1016/j.biocel.2017.01.012. Epub 2017 Jan 27. Int J Biochem Cell Biol. 2017. PMID: 28137482

10

Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.

Hohnholt MC, Andersen VH, Andersen JV, Christensen SK, Karaca M, Maechler P, Waagepetersen HS. Hohnholt MC, et al. Among authors: maechler p. J Cereb Blood Flow Metab. 2018 Oct;38(10):1754-1768. doi: 10.1177/0271678X17714680. Epub 2017 Jun 16. J Cereb Blood Flow Metab. 2018. PMID: 28621566 Free PMC article.

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