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Killing cells by targeting mitosis.
Manchado E, Guillamot M, Malumbres M. Manchado E, et al. Cell Death Differ. 2012 Mar;19(3):369-77. doi: 10.1038/cdd.2011.197. Epub 2012 Jan 6. Cell Death Differ. 2012. PMID: 22223105 Free PMC article. Review.
Targeting aneuploidy for cancer therapy.
Manchado E, Malumbres M. Manchado E, et al. Cell. 2011 Feb 18;144(4):465-6. doi: 10.1016/j.cell.2011.01.037. Cell. 2011. PMID: 21335229 Free article.
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.
Álvarez-Fernández M, Sanz-Flores M, Sanz-Castillo B, Salazar-Roa M, Partida D, Zapatero-Solana E, Ali HR, Manchado E, Lowe S, VanArsdale T, Shields D, Caldas C, Quintela-Fandino M, Malumbres M. Álvarez-Fernández M, et al. Among authors: manchado e. Cell Death Differ. 2018 May;25(5):828-840. doi: 10.1038/s41418-017-0024-0. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229993 Free PMC article.
Genomic stability and tumour suppression by the APC/C cofactor Cdh1.
García-Higuera I, Manchado E, Dubus P, Cañamero M, Méndez J, Moreno S, Malumbres M. García-Higuera I, et al. Among authors: manchado e. Nat Cell Biol. 2008 Jul;10(7):802-11. doi: 10.1038/ncb1742. Epub 2008 Jun 15. Nat Cell Biol. 2008. PMID: 18552834
Non-mitotic functions of the Anaphase-Promoting Complex.
Eguren M, Manchado E, Malumbres M. Eguren M, et al. Among authors: manchado e. Semin Cell Dev Biol. 2011 Aug;22(6):572-8. doi: 10.1016/j.semcdb.2011.03.010. Epub 2011 Mar 23. Semin Cell Dev Biol. 2011. PMID: 21439391 Review.
NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination.
Ruscetti M, Leibold J, Bott MJ, Fennell M, Kulick A, Salgado NR, Chen CC, Ho YJ, Sanchez-Rivera FJ, Feucht J, Baslan T, Tian S, Chen HA, Romesser PB, Poirier JT, Rudin CM, de Stanchina E, Manchado E, Sherr CJ, Lowe SW. Ruscetti M, et al. Among authors: manchado e. Science. 2018 Dec 21;362(6421):1416-1422. doi: 10.1126/science.aas9090. Science. 2018. PMID: 30573629 Free PMC article.
26 results