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Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.
Kjeldsen TB, Hubálek F, Hjørringgaard CU, Tagmose TM, Nishimura E, Stidsen CE, Porsgaard T, Fledelius C, Refsgaard HHF, Gram-Nielsen S, Naver H, Pridal L, Hoeg-Jensen T, Jeppesen CB, Manfè V, Ludvigsen S, Lautrup-Larsen I, Madsen P. Kjeldsen TB, et al. Among authors: manfe v. J Med Chem. 2021 Jul 8;64(13):8942-8950. doi: 10.1021/acs.jmedchem.1c00257. Epub 2021 May 4. J Med Chem. 2021. PMID: 33944562 Free article.
Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320.
Kjeldsen TB, Hubálek F, Tagmose TM, Pridal L, Refsgaard HHF, Porsgaard T, Gram-Nielsen S, Hovgaard L, Valore H, Münzel M, Hjørringgaard CU, Jeppesen CB, Manfè V, Hoeg-Jensen T, Ludvigsen S, Nielsen PK, Lautrup-Larsen I, Stidsen CE, Wulff EM, Garibay PW, Kodra JT, Nishimura E, Madsen P. Kjeldsen TB, et al. Among authors: manfe v. J Med Chem. 2021 Jan 14;64(1):616-628. doi: 10.1021/acs.jmedchem.0c01576. Epub 2020 Dec 28. J Med Chem. 2021. PMID: 33356257
Molecular Engineering of Efficacious Mono-Valent Ultra-Long Acting Two-Chain Insulin-Fc Conjugates.
Tagmose TM, Pedersen KM, Pridal L, Stidsen CE, Pedersen MØ, Lin Z, Zhang Y, Wan Z, Ferreras M, Naver H, Nielsen PK, Cao Z, Wang Y, Lykke L, Christensen JL, Jensen VS, Manfè V, Pedersen TÅ, Johansson E, Madsen P, Kodra JT, Münzel M, De Maria L, Nishimura E, Kjeldsen TB. Tagmose TM, et al. Among authors: manfe v. J Med Chem. 2022 Feb 10;65(3):2633-2645. doi: 10.1021/acs.jmedchem.1c02039. Epub 2022 Feb 1. J Med Chem. 2022. PMID: 35104142
A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?
Rakipovski G, Rolin B, Barascuk N, Lund HE, Bjørn Bonde MF, Djordjevic D, Wulff-Larsen PG, Petersen M, Kirk RK, Hultman K, Manfe V, Blume N, Zahn S, Lengquist M, Maegdefessel L, Hovingh GK, Conde-Knape K, Hedin U, Matic L, Nyberg M. Rakipovski G, et al. Among authors: manfe v. Atherosclerosis. 2020 Dec;314:1-9. doi: 10.1016/j.atherosclerosis.2020.10.001. Epub 2020 Oct 6. Atherosclerosis. 2020. PMID: 33129080
MicroRNA miR-125b induces senescence in human melanoma cells.
Glud M, Manfé V, Biskup E, Holst L, Dirksen AM, Hastrup N, Nielsen FC, Drzewiecki KT, Gniadecki R. Glud M, et al. Among authors: manfe v. Melanoma Res. 2011 Jun;21(3):253-6. doi: 10.1097/CMR.0b013e328345333b. Melanoma Res. 2011. PMID: 21460750
18 results