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Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard.
Rothmiller S, Jäger N, Meier N, Meyer T, Neu A, Steinritz D, Thiermann H, Scherer M, Rummel C, Mangerich A, Bürkle A, Schmidt A. Rothmiller S, et al. Among authors: mangerich a. Arch Toxicol. 2021 Feb;95(2):727-747. doi: 10.1007/s00204-020-02946-5. Epub 2021 Jan 25. Arch Toxicol. 2021. PMID: 33491125 Free PMC article.
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1.
Mangerich A, Herbach N, Hanf B, Fischbach A, Popp O, Moreno-Villanueva M, Bruns OT, Bürkle A. Mangerich A, et al. Mech Ageing Dev. 2010 Jun;131(6):389-404. doi: 10.1016/j.mad.2010.05.005. Epub 2010 Jun 8. Mech Ageing Dev. 2010. PMID: 20561897
PARP-1 is involved in the regulation of genomic integrity, transcription, inflammation, and cell death. Due to its versatile role, PARP-1 is discussed both as a longevity factor and as an aging-promoting factor. Recently, we generated a mouse model with ectopic inte …
PARP-1 is involved in the regulation of genomic integrity, transcription, inflammation, and cell death. Due to its versatile role, PARP-1 is …
64 results