Mannava S - Search Results

1

Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells.

Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA. Mannava S, et al. Cell Cycle. 2008 Aug;7(15):2392-400. doi: 10.4161/cc.6390. Epub 2008 Jun 3. Cell Cycle. 2008. PMID: 18677108 Free PMC article.

2

Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence.

Mannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE, Im M, Flanagan S, Burhans WC, Zeitouni NC, Shewach DS, Mathews CK, Nikiforov MA. Mannava S, et al. Am J Pathol. 2013 Jan;182(1):142-51. doi: 10.1016/j.ajpath.2012.09.011. Epub 2012 Dec 12. Am J Pathol. 2013. PMID: 23245831 Free PMC article.

3

Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion.

Mannava S, Moparthy KC, Wheeler LJ, Leonova KI, Wawrzyniak JA, Bianchi-Smiraglia A, Berman AE, Flanagan S, Shewach DS, Zeitouni NC, Gudkov AV, Mathews CK, Nikiforov MA. Mannava S, et al. Aging (Albany NY). 2012 Dec;4(12):917-22. doi: 10.18632/aging.100512. Aging (Albany NY). 2012. PMID: 23249808 Free PMC article.

4

A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.

Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, Mannava S, Ackroyd J, Bagati A, Omilian AR, Im M, Fedtsova N, Miecznikowski JC, Moparthy KC, Zucker SN, Zhu Q, Kozlova NI, Berman AE, Hoek KS, Gudkov AV, Shewach DS, Morrison CD, Nikiforov MA. Wawrzyniak JA, et al. Among authors: mannava s. Cell Rep. 2013 Oct 31;5(2):493-507. doi: 10.1016/j.celrep.2013.09.015. Epub 2013 Oct 17. Cell Rep. 2013. PMID: 24139804 Free PMC article.

5

C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells.

Zhuang D, Mannava S, Grachtchouk V, Tang WH, Patil S, Wawrzyniak JA, Berman AE, Giordano TJ, Prochownik EV, Soengas MS, Nikiforov MA. Zhuang D, et al. Among authors: mannava s. Oncogene. 2008 Nov 6;27(52):6623-34. doi: 10.1038/onc.2008.258. Epub 2008 Aug 4. Oncogene. 2008. PMID: 18679422 Free PMC article.

6

KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells.

Mannava S, Zhuang D, Nair JR, Bansal R, Wawrzyniak JA, Zucker SN, Fink EE, Moparthy KC, Hu Q, Liu S, Boise LH, Lee KP, Nikiforov MA. Mannava S, et al. Blood. 2012 Feb 9;119(6):1450-8. doi: 10.1182/blood-2011-04-346676. Epub 2011 Dec 5. Blood. 2012. PMID: 22144178 Free PMC article.

7

c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle.

Wang H, Mannava S, Grachtchouk V, Zhuang D, Soengas MS, Gudkov AV, Prochownik EV, Nikiforov MA. Wang H, et al. Among authors: mannava s. Oncogene. 2008 Mar 20;27(13):1905-15. doi: 10.1038/sj.onc.1210823. Epub 2007 Oct 1. Oncogene. 2008. PMID: 17906696 Free PMC article.

8

PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells.

Mannava S, Omilian AR, Wawrzyniak JA, Fink EE, Zhuang D, Miecznikowski JC, Marshall JR, Soengas MS, Sears RC, Morrison CD, Nikiforov MA. Mannava S, et al. Oncogene. 2012 Mar 22;31(12):1484-92. doi: 10.1038/onc.2011.339. Epub 2011 Aug 8. Oncogene. 2012. PMID: 21822300 Free PMC article.

9

Short hairpin RNA suppression of thymidylate synthase produces DNA mismatches and results in excellent radiosensitization.

Flanagan SA, Cooper KS, Mannava S, Nikiforov MA, Shewach DS. Flanagan SA, et al. Among authors: mannava s. Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):e613-20. doi: 10.1016/j.ijrobp.2012.06.050. Epub 2012 Aug 3. Int J Radiat Oncol Biol Phys. 2012. PMID: 22867891 Free PMC article.

10

Nrf2 amplifies oxidative stress via induction of Klf9.

Zucker SN, Fink EE, Bagati A, Mannava S, Bianchi-Smiraglia A, Bogner PN, Wawrzyniak JA, Foley C, Leonova KI, Grimm MJ, Moparthy K, Ionov Y, Wang J, Liu S, Sexton S, Kandel ES, Bakin AV, Zhang Y, Kaminski N, Segal BH, Nikiforov MA. Zucker SN, et al. Among authors: mannava s. Mol Cell. 2014 Mar 20;53(6):916-928. doi: 10.1016/j.molcel.2014.01.033. Epub 2014 Mar 6. Mol Cell. 2014. PMID: 24613345 Free PMC article.

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