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Page 1
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.
Lautenschläger J, Stephens AD, Fusco G, Ströhl F, Curry N, Zacharopoulou M, Michel CH, Laine R, Nespovitaya N, Fantham M, Pinotsi D, Zago W, Fraser P, Tandon A, St George-Hyslop P, Rees E, Phillips JJ, De Simone A, Kaminski CF, Schierle GSK. Lautenschläger J, et al. Among authors: fantham m. Nat Commun. 2018 Feb 19;9(1):712. doi: 10.1038/s41467-018-03111-4. Nat Commun. 2018. PMID: 29459792 Free PMC article.
Single particle trajectories reveal active endoplasmic reticulum luminal flow.
Holcman D, Parutto P, Chambers JE, Fantham M, Young LJ, Marciniak SJ, Kaminski CF, Ron D, Avezov E. Holcman D, et al. Among authors: fantham m. Nat Cell Biol. 2018 Oct;20(10):1118-1125. doi: 10.1038/s41556-018-0192-2. Epub 2018 Sep 17. Nat Cell Biol. 2018. PMID: 30224760 Free PMC article.
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies.
Lautenschläger J, Wagner-Valladolid S, Stephens AD, Fernández-Villegas A, Hockings C, Mishra A, Manton JD, Fantham MJ, Lu M, Rees EJ, Kaminski CF, Kaminski Schierle GS. Lautenschläger J, et al. Among authors: fantham mj. J Biol Chem. 2020 Jul 24;295(30):10138-10152. doi: 10.1074/jbc.RA119.011650. Epub 2020 May 8. J Biol Chem. 2020. PMID: 32385113 Free PMC article.
OptiJ: Open-source optical projection tomography of large organ samples.
Vallejo Ramirez PP, Zammit J, Vanderpoorten O, Riche F, Blé FX, Zhou XH, Spiridon B, Valentine C, Spasov SE, Oluwasanya PW, Goodfellow G, Fantham MJ, Siddiqui O, Alimagham F, Robbins M, Stretton A, Simatos D, Hadeler O, Rees EJ, Ströhl F, Laine RF, Kaminski CF. Vallejo Ramirez PP, et al. Among authors: fantham mj. Sci Rep. 2019 Oct 30;9(1):15693. doi: 10.1038/s41598-019-52065-0. Sci Rep. 2019. PMID: 31666606 Free PMC article.