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Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells.
Morris V, Wang D, Li Z, Marion W, Hughes T, Sousa P, Harada T, Sui SH, Naumenko S, Kalfon J, Sensharma P, Falchetti M, Vinicius da Silva R, Candelli T, Schneider P, Margaritis T, Holstege FCP, Pikman Y, Harris M, Stam RW, Orkin SH, Koehler AN, Shalek AK, North TE, Pimkin M, Daley GQ, Lummertz da Rocha E, Rowe RG. Morris V, et al. Among authors: margaritis t. Cell Rep. 2022 Apr 26;39(4):110752. doi: 10.1016/j.celrep.2022.110752. Cell Rep. 2022. PMID: 35476984 Free PMC article.
Poised RNA polymerase II gives pause for thought.
Margaritis T, Holstege FC. Margaritis T, et al. Cell. 2008 May 16;133(4):581-4. doi: 10.1016/j.cell.2008.04.027. Cell. 2008. PMID: 18485867 Free article. Review.
Functional overlap and regulatory links shape genetic interactions between signaling pathways.
van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC. van Wageningen S, et al. Among authors: margaritis t. Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021. Cell. 2010. PMID: 21145464 Free PMC article.
The specificity and topology of chromatin interaction pathways in yeast.
Lenstra TL, Benschop JJ, Kim T, Schulze JM, Brabers NA, Margaritis T, van de Pasch LA, van Heesch SA, Brok MO, Groot Koerkamp MJ, Ko CW, van Leenen D, Sameith K, van Hooff SR, Lijnzaad P, Kemmeren P, Hentrich T, Kobor MS, Buratowski S, Holstege FC. Lenstra TL, et al. Among authors: margaritis t. Mol Cell. 2011 May 20;42(4):536-49. doi: 10.1016/j.molcel.2011.03.026. Mol Cell. 2011. PMID: 21596317 Free PMC article.
Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.
Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC. Kemmeren P, et al. Among authors: margaritis t. Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054. Cell. 2014. PMID: 24766815 Free article.
Cell cycle population effects in perturbation studies.
O'Duibhir E, Lijnzaad P, Benschop JJ, Lenstra TL, van Leenen D, Groot Koerkamp MJ, Margaritis T, Brok MO, Kemmeren P, Holstege FC. O'Duibhir E, et al. Among authors: margaritis t. Mol Syst Biol. 2014 Jun 21;10(6):732. doi: 10.15252/msb.20145172. Mol Syst Biol. 2014. PMID: 24952590 Free PMC article.
30 results