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CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3.
Neoplasia. 2020 Jan;22(1):47-59. doi: 10.1016/j.neo.2019.10.002. Epub 2019 Nov 22.
Neoplasia. 2020.
PMID: 31765941
Free PMC article.
Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses.
Brown JR, Walker SR, Heppler LN, Tyekucheva S, Nelson EA, Klitgaard J, Nicolais M, Kroll Y, Xiang M, Yeh JE, Chaudhury M, Giaccone ZT, Fernandes SM, Jacobsen ED, Fisher DC, Freedman AS, Davids MS, Supko JG, Wu C, Frank DA.
Brown JR, et al. Among authors: nicolais m.
Am J Hematol. 2021 Apr 1;96(4):E95-E98. doi: 10.1002/ajh.26084. Epub 2021 Jan 11.
Am J Hematol. 2021.
PMID: 33373063
Free PMC article.
Clinical Trial.
No abstract available.
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Selective Akt inhibitors synergize with tyrosine kinase inhibitors and effectively override stroma-associated cytoprotection of mutant FLT3-positive AML cells.
Weisberg E, Liu Q, Zhang X, Nelson E, Sattler M, Liu F, Nicolais M, Zhang J, Mitsiades C, Smith RW, Stone R, Galinsky I, Nonami A, Griffin JD, Gray N.
Weisberg E, et al. Among authors: nicolais m.
PLoS One. 2013;8(2):e56473. doi: 10.1371/journal.pone.0056473. Epub 2013 Feb 21.
PLoS One. 2013.
PMID: 23437141
Free PMC article.
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The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations.
Nelson EA, Walker SR, Xiang M, Weisberg E, Bar-Natan M, Barrett R, Liu S, Kharbanda S, Christie AL, Nicolais M, Griffin JD, Stone RM, Kung AL, Frank DA.
Nelson EA, et al. Among authors: nicolais m.
Genes Cancer. 2012 Jul;3(7-8):503-11. doi: 10.1177/1947601912466555.
Genes Cancer. 2012.
PMID: 23264850
Free PMC article.
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