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Lhs1 dependent ERAD is determined by transmembrane domain context.
Sukhoplyasova M, Keith AM, Perrault EM, Vorndran HE, Jordahl AS, Yates ME, Pastor A, Li Z, Freaney ML, Deshpande RA, Adams DB, Guerriero CJ, Shi S, Kleyman TR, Kashlan OB, Brodsky JL, Buck TM. Sukhoplyasova M, et al. Biochem J. 2023 Sep 27;480(18):1459-1473. doi: 10.1042/BCJ20230075. Biochem J. 2023. PMID: 37702403
Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum functions.
Mann MJ, Melendez-Suchi C, Sukhoplyasova M, Flory AR, Carson Irvine M, Iyer AR, Vorndran H, Guerriero CJ, Brodsky JL, Hendershot LM, Buck TM. Mann MJ, et al. Among authors: sukhoplyasova m. bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563191. doi: 10.1101/2023.10.19.563191. bioRxiv. 2023. PMID: 37905119 Free PMC article. Updated. Preprint.
Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum function.
Mann MJ, Melendez-Suchi C, Vorndran HE, Sukhoplyasova M, Flory AR, Irvine MC, Iyer AR, Guerriero CJ, Brodsky JL, Hendershot LM, Buck TM. Mann MJ, et al. Among authors: sukhoplyasova m. Mol Biol Cell. 2024 Apr 1;35(4):ar59. doi: 10.1091/mbc.E24-01-0012. Epub 2024 Mar 6. Mol Biol Cell. 2024. PMID: 38446639