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Clonality in haematopoietic stem cell ageing.
Terradas-Terradas M, Robertson NA, Chandra T, Kirschner K. Terradas-Terradas M, et al. Mech Ageing Dev. 2020 Jul;189:111279. doi: 10.1016/j.mad.2020.111279. Epub 2020 Jun 8. Mech Ageing Dev. 2020. PMID: 32526214 Free PMC article. Review.
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Robertson NA, Latorre-Crespo E, Terradas-Terradas M, Lemos-Portela J, Purcell AC, Livesey BJ, Hillary RF, Murphy L, Fawkes A, MacGillivray L, Copland M, Marioni RE, Marsh JA, Harris SE, Cox SR, Deary IJ, Schumacher LJ, Kirschner K, Chandra T. Robertson NA, et al. Among authors: terradas terradas m. Nat Med. 2022 Jul;28(7):1439-1446. doi: 10.1038/s41591-022-01883-3. Epub 2022 Jul 4. Nat Med. 2022. PMID: 35788175 Free PMC article.
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Latif AL, Newcombe A, Li S, Gilroy K, Robertson NA, Lei X, Stewart HJS, Cole J, Terradas MT, Rishi L, McGarry L, McKeeve C, Reid C, Clark W, Campos J, Kirschner K, Davis A, Lopez J, Sakamaki JI, Morton JP, Ryan KM, Tait SWG, Abraham SA, Holyoake T, Higgins B, Huang X, Blyth K, Copland M, Chevassut TJT, Keeshan K, Adams PD. Latif AL, et al. Among authors: terradas mt. Nat Commun. 2021 Jan 11;12(1):241. doi: 10.1038/s41467-020-20378-8. Nat Commun. 2021. PMID: 33431824 Free PMC article.
Age-related clonal haemopoiesis is associated with increased epigenetic age.
Robertson NA, Hillary RF, McCartney DL, Terradas-Terradas M, Higham J, Sproul D, Deary IJ, Kirschner K, Marioni RE, Chandra T. Robertson NA, et al. Among authors: terradas terradas m. Curr Biol. 2019 Aug 19;29(16):R786-R787. doi: 10.1016/j.cub.2019.07.011. Curr Biol. 2019. PMID: 31430471 Free article.