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CARM1 regulates replication fork speed and stress response by stimulating PARP1.
Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. Genois MM, et al. Mol Cell. 2021 Feb 18;81(4):784-800.e8. doi: 10.1016/j.molcel.2020.12.010. Epub 2021 Jan 6. Mol Cell. 2021. PMID: 33412112 Free PMC article.
Targeting the DNA replication stress phenotype of KRAS mutant cancer cells.
Al Zubaidi T, Gehrisch OHF, Genois MM, Liu Q, Lu S, Kung J, Xie Y, Schuemann J, Lu HM, Hata AN, Zou L, Borgmann K, Willers H. Al Zubaidi T, et al. Among authors: genois mm. Sci Rep. 2021 Feb 11;11(1):3656. doi: 10.1038/s41598-021-83142-y. Sci Rep. 2021. PMID: 33574444 Free PMC article.
ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
Yazinski SA, Comaills V, Buisson R, Genois MM, Nguyen HD, Ho CK, Todorova Kwan T, Morris R, Lauffer S, Nussenzweig A, Ramaswamy S, Benes CH, Haber DA, Maheswaran S, Birrer MJ, Zou L. Yazinski SA, et al. Among authors: genois mm. Genes Dev. 2017 Feb 1;31(3):318-332. doi: 10.1101/gad.290957.116. Epub 2017 Feb 27. Genes Dev. 2017. PMID: 28242626 Free PMC article.
15 results