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EMRE is an essential component of the mitochondrial calcium uniporter complex.
Sancak Y, Markhard AL, Kitami T, Kovács-Bogdán E, Kamer KJ, Udeshi ND, Carr SA, Chaudhuri D, Clapham DE, Li AA, Calvo SE, Goldberger O, Mootha VK. Sancak Y, et al. Among authors: markhard al. Science. 2013 Dec 13;342(6164):1379-82. doi: 10.1126/science.1242993. Epub 2013 Nov 14. Science. 2013. PMID: 24231807 Free PMC article.
Architecture of the mitochondrial calcium uniporter.
Oxenoid K, Dong Y, Cao C, Cui T, Sancak Y, Markhard AL, Grabarek Z, Kong L, Liu Z, Ouyang B, Cong Y, Mootha VK, Chou JJ. Oxenoid K, et al. Among authors: markhard al. Nature. 2016 May 12;533(7602):269-73. doi: 10.1038/nature17656. Epub 2016 May 2. Nature. 2016. PMID: 27135929 Free PMC article.
Hepatic NADH reductive stress underlies common variation in metabolic traits.
Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, Kim JK, Mootha VK. Goodman RP, et al. Among authors: markhard al. Nature. 2020 Jul;583(7814):122-126. doi: 10.1038/s41586-020-2337-2. Epub 2020 May 27. Nature. 2020. PMID: 32461692 Free PMC article.
Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation.
Ganetzky RD, Markhard AL, Yee I, Clever S, Cahill A, Shah H, Grabarek Z, To TL, Mootha VK. Ganetzky RD, et al. Among authors: markhard al. N Engl J Med. 2022 Oct 13;387(15):1395-1403. doi: 10.1056/NEJMoa2202949. N Engl J Med. 2022. PMID: 36239646 Free PMC article.
Hypoxia extends lifespan and neurological function in a mouse model of aging.
Rogers RS, Wang H, Durham TJ, Stefely JA, Owiti NA, Markhard AL, Sandler L, To TL, Mootha VK. Rogers RS, et al. Among authors: markhard al. PLoS Biol. 2023 May 23;21(5):e3002117. doi: 10.1371/journal.pbio.3002117. eCollection 2023 May. PLoS Biol. 2023. PMID: 37220109 Free PMC article.
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF, Markhard AL, Sabatini DM. Sarbassov DD, et al. Among authors: markhard al. Mol Cell. 2006 Apr 21;22(2):159-68. doi: 10.1016/j.molcel.2006.03.029. Epub 2006 Apr 6. Mol Cell. 2006. PMID: 16603397 Free article.
15 results