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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 3
2003 1
2004 4
2005 2
2006 3
2007 2
2008 1
2009 3
2010 1
2011 3
2012 3
2013 2
2014 4
2015 4
2016 5
2017 4
2018 2
2019 7
2020 7
2021 6
2022 7
2023 10
2024 3

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75 results

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Page 1
Quantitative mass spectrometry in proteomics: a critical review.
Bantscheff M, Schirle M, Sweetman G, Rick J, Kuster B. Bantscheff M, et al. Among authors: schirle m. Anal Bioanal Chem. 2007 Oct;389(4):1017-31. doi: 10.1007/s00216-007-1486-6. Epub 2007 Aug 1. Anal Bioanal Chem. 2007. PMID: 17668192 Free article. Review.
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, Frank AO, Fuller D, Estes AR, Randal KL, Panidapu A, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Henning NJ, et al. Among authors: schirle m. Nat Chem Biol. 2022 Apr;18(4):412-421. doi: 10.1038/s41589-022-00971-2. Epub 2022 Feb 24. Nat Chem Biol. 2022. PMID: 35210618 Free PMC article.
Rational Chemical Design of Molecular Glue Degraders.
Toriki ES, Papatzimas JW, Nishikawa K, Dovala D, Frank AO, Hesse MJ, Dankova D, Song JG, Bruce-Smythe M, Struble H, Garcia FJ, Brittain SM, Kile AC, McGregor LM, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Toriki ES, et al. Among authors: schirle m. ACS Cent Sci. 2023 Apr 11;9(5):915-926. doi: 10.1021/acscentsci.2c01317. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252349 Free PMC article.
Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.
Fischer ES, Böhm K, Lydeard JR, Yang H, Stadler MB, Cavadini S, Nagel J, Serluca F, Acker V, Lingaraju GM, Tichkule RB, Schebesta M, Forrester WC, Schirle M, Hassiepen U, Ottl J, Hild M, Beckwith RE, Harper JW, Jenkins JL, Thomä NH. Fischer ES, et al. Among authors: schirle m. Nature. 2014 Aug 7;512(7512):49-53. doi: 10.1038/nature13527. Epub 2014 Jul 16. Nature. 2014. PMID: 25043012 Free PMC article.
Targeted Protein Degradation through E2 Recruitment.
Forte N, Dovala D, Hesse MJ, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Forte N, et al. Among authors: schirle m. ACS Chem Biol. 2023 Apr 21;18(4):897-904. doi: 10.1021/acschembio.3c00040. Epub 2023 Mar 20. ACS Chem Biol. 2023. PMID: 36940189 Free PMC article.
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F. Huang SM, et al. Among authors: schirle m. Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16. Nature. 2009. PMID: 19759537
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Dowdle WE, Nyfeler B, Nagel J, Elling RA, Liu S, Triantafellow E, Menon S, Wang Z, Honda A, Pardee G, Cantwell J, Luu C, Cornella-Taracido I, Harrington E, Fekkes P, Lei H, Fang Q, Digan ME, Burdick D, Powers AF, Helliwell SB, D'Aquin S, Bastien J, Wang H, Wiederschain D, Kuerth J, Bergman P, Schwalb D, Thomas J, Ugwonali S, Harbinski F, Tallarico J, Wilson CJ, Myer VE, Porter JA, Bussiere DE, Finan PM, Labow MA, Mao X, Hamann LG, Manning BD, Valdez RA, Nicholson T, Schirle M, Knapp MS, Keaney EP, Murphy LO. Dowdle WE, et al. Among authors: schirle m. Nat Cell Biol. 2014 Nov;16(11):1069-79. doi: 10.1038/ncb3053. Epub 2014 Oct 19. Nat Cell Biol. 2014. PMID: 25327288
Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control.
Gurzeler LA, Link M, Ibig Y, Schmidt I, Galuba O, Schoenbett J, Gasser-Didierlaurant C, Parker CN, Mao X, Bitsch F, Schirle M, Couttet P, Sigoillot F, Ziegelmüller J, Uldry AC, Teodorowicz W, Schmiedeberg N, Mühlemann O, Reinhardt J. Gurzeler LA, et al. Among authors: schirle m. Cell Rep. 2023 Sep 26;42(9):113056. doi: 10.1016/j.celrep.2023.113056. Epub 2023 Aug 30. Cell Rep. 2023. PMID: 37651229 Free article.
75 results