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2022 2
2023 4
2024 0

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Page 1
Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer.
Naulaerts S, Datsi A, Borras DM, Antoranz Martinez A, Messiaen J, Vanmeerbeek I, Sprooten J, Laureano RS, Govaerts J, Panovska D, Derweduwe M, Sabel MC, Rapp M, Ni W, Mackay S, Van Herck Y, Gelens L, Venken T, More S, Bechter O, Bergers G, Liston A, De Vleeschouwer S, Van Den Eynde BJ, Lambrechts D, Verfaillie M, Bosisio F, Tejpar S, Borst J, Sorg RV, De Smet F, Garg AD. Naulaerts S, et al. Among authors: derweduwe m. Sci Transl Med. 2023 Apr 12;15(691):eadd1016. doi: 10.1126/scitranslmed.add1016. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043555
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto L, Cole B, Giese W, Baumann E, Claeys A, Vanmechelen M, Decraene B, Derweduwe M, Dubroja Lakic N, Shankar G, Nagathihalli Kantharaju M, Albrecht JP, Geudens I, Stanchi F, Ligon KL, Boeckx B, Lambrechts D, Harrington K, Van Den Bosch L, De Vleeschouwer S, De Smet F, Gerhardt H. Finotto L, et al. Among authors: derweduwe m. EMBO Mol Med. 2023 Nov 8;15(11):e18144. doi: 10.15252/emmm.202318144. Epub 2023 Oct 4. EMBO Mol Med. 2023. PMID: 37791581 Free PMC article.
Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma.
Panovska D, Nazari P, Cole B, Creemers PJ, Derweduwe M, Solie L, Van Gassen S, Claeys A, Verbeke T, Cohen EF, Tolstorukov MY, Saeys Y, Van der Planken D, Bosisio FM, Put E, Bamps S, Clement PM, Verfaillie M, Sciot R, Ligon KL, De Vleeschouwer S, Antoranz A, De Smet F. Panovska D, et al. Among authors: derweduwe m. Cell Mol Life Sci. 2023 May 12;80(6):147. doi: 10.1007/s00018-023-04772-1. Cell Mol Life Sci. 2023. PMID: 37171617
Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion.
Messiaen J, Claeys A, Shetty A, Spans L, Derweduwe M, Uyttebroeck A, Depreitere B, Vanden Bempt I, Sciot R, Ligon KL, Jones DTW, Jacobs SA, De Smet F. Messiaen J, et al. Among authors: derweduwe m. Acta Neuropathol. 2022 Oct;144(4):793-797. doi: 10.1007/s00401-022-02473-w. Epub 2022 Aug 4. Acta Neuropathol. 2022. PMID: 35925403 Free PMC article. No abstract available.
Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation.
Naus E, Derweduwe M, Lampi Y, Claeys A, Pauwels J, Langenberg T, Claes F, Xu J, Haemels V, Atak ZK, van der Kant R, Van Durme J, De Baets G, Ligon KL, Fiers M, Gevaert K, Aerts S, Rousseau F, Schymkowitz J, De Smet F. Naus E, et al. Among authors: derweduwe m. Cells. 2023 Mar 21;12(6):960. doi: 10.3390/cells12060960. Cells. 2023. PMID: 36980299 Free PMC article.
GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide.
Parik S, Fernández-García J, Lodi F, De Vlaminck K, Derweduwe M, De Vleeschouwer S, Sciot R, Geens W, Weng L, Bosisio FM, Bergers G, Duerinck J, De Smet F, Lambrechts D, Van Ginderachter JA, Fendt SM. Parik S, et al. Among authors: derweduwe m. Front Oncol. 2022 Sep 23;12:988872. doi: 10.3389/fonc.2022.988872. eCollection 2022. Front Oncol. 2022. PMID: 36338708 Free PMC article.