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SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence.
Gioia U, Tavella S, Martínez-Orellana P, Cicio G, Colliva A, Ceccon M, Cabrini M, Henriques AC, Fumagalli V, Paldino A, Presot E, Rajasekharan S, Iacomino N, Pisati F, Matti V, Sepe S, Conte MI, Barozzi S, Lavagnino Z, Carletti T, Volpe MC, Cavalcante P, Iannacone M, Rampazzo C, Bussani R, Tripodo C, Zacchigna S, Marcello A, d'Adda di Fagagna F. Gioia U, et al. Among authors: ceccon m. Nat Cell Biol. 2023 Apr;25(4):550-564. doi: 10.1038/s41556-023-01096-x. Epub 2023 Mar 9. Nat Cell Biol. 2023. PMID: 36894671 Free PMC article.
DNA Damage Triggers a New Phase in Neurodegeneration.
Pessina F, Gioia U, Brandi O, Farina S, Ceccon M, Francia S, d'Adda di Fagagna F. Pessina F, et al. Among authors: ceccon m. Trends Genet. 2021 Apr;37(4):337-354. doi: 10.1016/j.tig.2020.09.006. Epub 2020 Oct 2. Trends Genet. 2021. PMID: 33020022 Free article. Review.
Crystal structures and atomic model of NADPH oxidase.
Magnani F, Nenci S, Millana Fananas E, Ceccon M, Romero E, Fraaije MW, Mattevi A. Magnani F, et al. Among authors: ceccon m. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6764-6769. doi: 10.1073/pnas.1702293114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607049 Free PMC article.